Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems.
Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting.
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Part A Anatomy and physiology of the brain
1. An overview of the anatomy and physiology of the brain
2. Blood-brain barrier and central nervous system drug delivery: Opportunities and challenges
Part B Pharmacological and clinical problems
3.Challenges in targeting to brain and brain tumors
4. Potential targeting sites in brain and brain tumors
5. Drug resistance problems in chemotherapy
Part C Introduction and biomedical applications of nanocarriers
6. An overview on nanocarriers
7. Biomedical applications of nanocarriers in brain tumor targeting
Part D Lipophilic nanocarriers
8. Solid lipid nanoparticle-based drug delivery for targeting brain tumors
9. Nanostructured lipid carriers as an alternative carrier with high drug loading for targeting to brain tumors
10. Design, development, and mechanism of liposomes in drug targeting to brain tumors
11. Niosomes based drug delivery in targeting brain tumors
12. Nanoemulsions as effective carriers for targeting brain tumors
Part E Polymeric nanocarriers
13. Mechanism of polymeric micelles for drug targeting to brain tumors
14. Dendrimers as carriers for active targeting of brain tumors
15. Multifunctional polymeric nanocarriers for targeting and treatment of brain tumors
16. Polymersomes for targeting to brain tumors
Part F Metallic nanocarriers systems
17. Development and applications of gold nanoparticles for drug targeting to brain tumors
18. Gold nanoparticles in cancer theranostics
19. Targeting of silver nanoparticles to brain tumors
Part G Hybrid nanocarriers
20. Hybrid nanoparticles to cross the blood–brain barrier
21. Targeting of lipid-polymer (hybrid) nanoparticles to brain tumors
22. Nano-enabled systems for neural tissue regenerative applications
23. Multifunctional liposome-quantum dot hybrid nanocarriers for drug targeting to brain tumors
24. Drug-loaded nanoclusters for brain targeting
25. Nano-enabled platforms for tropical diseases affecting the CNS
26. Phytoconstituents in brain delivery using nanodrug delivery
27. Multifunctional nanocarrier systems targeting brain tumors: A review
Part H Future directions and toxic concerns
28. Expert opinion on current challenges and future directions related to nanocarriers for drug targeting to the brain
29. Biological nanodrugs for brain targeting
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Provides information on the major nanomaterial types used for drug targeting and delivery to combat brain tumors
Provides information on the design and development of nanocarriers for targeting brain tumors
Outlines the working principles of different nanocarriers for targeting brain tumors
Includes case studies of different nanocarriers for targeting brain tumors
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Produktdetaljer
ISBN
9780323907736
Publisert
2022-06-23
Utgiver
Vendor
Elsevier - Health Sciences Division
Vekt
450 gr
Høyde
235 mm
Bredde
191 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
856