This book constitutes refereed proceedings of the 15th International Conference on Parallel Computational Technologies, PCT 2021, held in March-April 2021. Due to the COVID-19 pandemic the conference was held online.The 22 revised full papers presented were carefully reviewed and selected from 89 submissions.

High Performance Architectures, Tools and Technologies.- Equivalent Transformations of Some Kinds of Computing Structures of Non-linear Recurrent Expressions for Reconfigurable Computing Systems.- Development and Practical Application of Methods for Detecting Similar Supercomputer Jobs.- Detecting Changes in Communication Properties of Parallel Programs by InfiniBand Traffic Analysis.- Transformation of Graphs with Associative Operations in Terms of the Set@l Programming Language.- Parallel Numerical Algorithms.- GPU-Accelerated Fuzzy Inference Based on Fuzzy Truth Values.- Deflation of Periodic Orbits in Large-Scale Systems: Algorithm and Parallel Implementation.- Parallel Computations for Solving Multicriteria Mixed-Integer Optimization Problems.- Parallel Intelligent Computing in Algebraic Problems.- CUDA Implementation of an Algorithm for Batch Mode Detection of Collisions.- Functionally Arranged Data for Algorithms with Space-Time Wavefront.- Exploring the Limitsof Problem-Specific Adaptations of SAT Solvers in SAT-based Cryptanalysis.- FRaGenLP: A Generator of Random Linear Programming Problems for Cluster Computing Systems.- Application of the AmgX Library to the Discontinuous Galerkin Methods for Elliptic Problems.- Conjugate Direction Methods for Parallel Deflation.- Supercomputer Simulation.- Research of the Mechanism of External Hormonal Regulation of the Development of Phyto- and Zooplankton Populations Using Supercomputer Technologies.- Luthien: A Parallel PIC Code for Modeling the Interaction of Focused Electron Beams with Plasma.- Simulation of Heat and Mass Transfer in Open Geothermal Systems: a Parallel Implementation.- Supercomputer-based Simulation of the Hydrodynamics of River Mouth Areas.- System for the Visualization of Meshes of Big Size Obtained from Gas-Dynamic Simulations.- Finite Element Simulation of the Influence of the Bending Roll Profile on the Stress-strain State of Billets for Longitudinal-welded Rolled Pipes.- Digital Twins of Geological Objects: Development and Use.- A Parallel Algorithm to Compute the Transport of Suspended Particles Based on 3D Models.

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