This two volume set constitutes the refereed post-conference proceedings of the Second International Conference on Machine Learning and Intelligent Communications, MLICOM 2017, held in Weihai, China, in August 2017. The 143 revised full papers were carefully selected from 225 submissions. The papers are organized thematically in machine learning, intelligent positioning and navigation, intelligent multimedia processing and security, intelligent wireless mobile network and security, cognitive radio and intelligent networking, intelligent internet of things, intelligent satellite communications and networking, intelligent remote sensing, visual computing and three-dimensional modeling, green communication and intelligent networking, intelligent ad-hoc and sensor networks, intelligent resource allocation in wireless and cloud networks, intelligent signal processing in wireless and optical communications, intelligent radar signal processing, intelligent cooperative communications and networking.