This book constitutes the thoroughly refereed post-conference proceedings of the 6th IFIP WG 13.6 Working Conference on Human Work Interaction Design, HWID 2021, held in Beijing, China, in May, 2021. The 10 revised and extended full papers presented were carefully selected for inclusion in this volume.

Trends in human Work Interaction Design.- Drifting towards a New HCI Field: A Review of 10 Years of HWID Research.- Organized UX Professionalism - An Empirical Study and Conceptual Tool for Scrutinizing UX Work of the Future.- Research on the Integration of Human-Computer Interaction and Cognitive Neuroscience.- HCI Four Waves within Different Interaction Design Examples.- Workplace & work experience Analysis for Interaction Design.- Design and Deployment Considerations for Ethically Advanced Technologies for Human Flourishing in the Workplace.- The Influence of Automation and Culture on Human Cooperation.- A Socio-technical Framework for Addressing the Influence of Work Time and Income on Work Wellbeing.- Co-Designing Prototypes for User Experience and Engagement in Automation.- Artificial Intelligence (AI) for Human Work.- Mood-Based Song Recommendation System.- Currency Recognition App for Visually Impaired Users in India.