Constitutes the refereed proceedings of the 6th International Conference on Computational Science, ICCS 2006. This book features 98 revised full papers and 29 revised poster papers of the main track. It spans the whole range of computational science.

Keynote Abstracts.- Modelling and Simulation in Economics and Finance.- Modelling and Simulation of Complex Systems and in the Natural Sciences.- Modelling and Simulation of Complex Systems.- Advanced Numerical Algorithms.- Data Driven Computing.- Advanced Numerical Algorithms and New Algorithmic Approaches to Computational Kernels and Applications.- Modelling and Simulation in the Natural Sciences.- Modelling and Simulation in the Natural Sciences.- Advanced Numerical Algorithms.- Applications of Computing as a Scientific Paradigm.- Applications of Computing as a Scientific Paradigm.- Modelling and Simulation in Engineering.- Modelling and Simulation in Engineering.- Parallel and Distributed Algorithms.- Other Aspects of Computational Science.- Computational Science Aspects of Data Mining and Information Retrieval.- Hybrid Computational Methods and New Algorithmic Approaches to Computational Kernels and Applications.- Simulations and Systems.- Advances in Parameter Estimation in Computational-Science: Strategies, Concepts, and Applications.- Efficient Fault Tolerance Techniques for Large Scale Systems.- Poster Session I.- Poster Session II.