This book constitutes the thoroughly refereed conference proceedings of the International Conference for Smart Health, ICSH 2019, held in Shenzhen, China, in July 2019. The 34 full papers and 1 short papers presented were carefully reviewed and selected from 43 submissions. In this book  a lively exchange and collaborations between the growing international smart health research scholars and communities has been introduced, and to advance our understanding about the technical, practical, economic, behavioral, and social issues center on smart health . The selected papers are organized into the following topics: Precision Medicine and Telehealth, Social, Psychosocial and Behavioral Determinants of Health, Data science, Analytics, Clinical and Business Intelligence, Clinical Informatics and Clinician Engagement.