This book constitutes the refereed proceedings of the 21st International Conference on Services Computing – SCC 2024, Held as Part of the Services Conference Federation, SCF 2024, held in Bangkok, Thailand, during November 16-19, 2024.The 7 full papers in this book were carefully reviewed and selected from 13 submissions.

.- Extracting Tuple-Based Service Demands With Large Language Models for Automated Service Composition. .- Revolutionizing Pharmaceutical Integrity: Using Smart Contracts and NFT Encryption to Safeguard Against Counterfeit Drugs. .- Comparative Analysis of EVM-Supported Blockchain Platforms for Enhancing Organ Donation Supply Chain Management. .- Proof of Stake Verifiers (PoSV) Consensus Mechanisms Implementation in AI Value Protocol (AIVP). .- Blockchain-Based Insurance Claim Management: Implementing RSA-Encrypted NFTs for Secure and Transparent Processing. .- COSIS: An AI-Enabled Digital Transformation Framework Integrating Large Language Models and Key Performance Indicators. .- Exploring Experiential Marketing Strategies of Luxury Fashion Brands in the Metaverse: An In-Depth Analysis of Immersive Consumer Engagement.