This book contains extended versions of the best papers presented at the 15th International Conference on Information and Communication Technologies in Education, Research, and Industrial Applications, ICTERI 2019, held in Kherson, Ukraine, in June 2019.The 19 revised full papers included in this volume were carefully reviewed and selected from 416 initial submissions. The papers are organized in the following topical sections: ​advances in ICT and IS research; ICT in teaching, learning, and education management; applications of ICT in industrial and public practice.