The mental health and well-being of health professionals is a topic that is broad, exceptionally relevant, and urgent to address. It is both a local and a global issue, and affects professionals in all stages of their careers. To explore this topic, the Global Forum on Innovation in Health Professional Education held a 1.5 day workshop. This publication summarizes the presentations and discussions from the workshop.Table of ContentsFront Matter1 A Design Thinking, Systems Approach to Well-Being2 Creating a Culture of Well-Being3 Breakout Session Discussions4 Leadership in Organizational Resilience5 Building on the Lessons LearnedAppendix A: Workshop AgendaAppendix B: The Importance of Well-Being in the Health Care WorkforceAppendix C: Listening to LeadershipAppendix D: Speaker Biographical SketchesAppendix E: Forum-Sponsored Products