Microbiota-Gut-Brain Axis and CNS Disorders: Recent Progress and Perspectives on Human Disease summarizes the main findings on gut-brain axis in different types of CNS disorders, providing a complete overview of the field. The content helps unravel the complex interactions of the microbiota-gut-brain-axis in CNS disorders to pave a better understanding of microbiota-mediated pathogenesis, avenues for noninvasive prognosis, and therapeutic possibilities leveraging microbiota-gut-brain-axis modulations. Coverage includes the role of the microbiota-gut-brain axis and gut virome on human diseases including Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, Depression and Anxiety, Autism Spectrum Disorder, Multiple Sclerosis, Stroke, and others. This book will satisfy the urgent need for a broader view of the current associations between gut microbiota alterations and development of CNS disorders, including the use of novel therapeutic approaches for restoring the correct intestinal bacteria content. It is the perfect reference for translational and clinical gut and microbiome researchers tackling the challenges of delivering genes and drugs in a more targeted and efficient manner for the treatment of CNS disorders.
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1. Introduction: An overview of Microbiota-Gut- Brain Axis 2. Role of Microbiota-Gut- Brain Axis in Alzheimer disease and possible interventions 3. Role of Microbiota Gut- Brain axis in Parkinson’s disease 4. Role of Microbiota-Gut- Brain Axis in Huntington’s disease and possible interventions 5. Role of Microbiota-Gut- Brain Axis in depression and anxiety 6. Role of microbiome- Gut Brain axis in autism spectrum disorder (ASD) 7. Role of Microbiota- Gut brain axis in autoimmunity and Multiple Sclerosis 8. Role of Microbiome Gut- Brain axis in stress 9. Role of Microbiota- Gut Brain Axis in epilepsy and possible interventions 10. Role of Microbiota- Gut Brain Axis in migraine and possible interventions 11. Role of Microbiota- Gut Brain Axis in stroke and possible interventions 12. Role of Microbiota- Gut Brain Axis in brain infections and possible interventions 13. Role of Microbiome Gut- Brain axis in brain disorders 14. Role of GUT microbiota in neuropsychiatric and neurological disorders 15. Role of Microbiota- Gut Brain Axis in Obesity on Cognitive Functions and Mood 16. Role of Microbiota- Gut Brain Axis on Neurotransmitters modulation 17. Role of gut virome and mycobiome in neurological disorders 18. Role of nutraceuticals in neurological diseases 19. Future prospective of Microbiome- Gut brain axis for treatment of CNS disorders
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Covers the microbiota-gut-brain-axis in CNS disorders to provide an understanding of pathogenesis, avenues for noninvasive prognosis, and therapeutic possibilities
Discusses the development of both health and disease in interdisciplinary research involving gut microbiology Provides an understanding the role of Microbiome-Gut-Brain axis in neurodegenerative and neurodevelopmental diseases, including central nervous system (CNS) malignancies Delivers a compilation of current clinical studies to further investigate the role of diet in varying neurological disorders
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Produktdetaljer

ISBN
9780443216800
Publisert
2025-01-29
Utgiver
Elsevier Science Publishing Co Inc; Academic Press Inc
Vekt
1050 gr
Høyde
235 mm
Bredde
191 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
514

Om bidragsyterne

Dr. Mishra is working as Professor in Amity Institute of Pharmacy, Gwalior since July 2019. He has around twenty-two years of teaching and research experience. He has more than 140 publications of International and National repute in recent concepts of novel drug delivery systems, localized drug delivery, targeted and controlled drug delivery of nanocarriers/ microparticles for the treatment of breast, colon cancer, and neurodegenerative disorders. Dr. Mishra more than 4100 citations with h- index 36. The total cumulative Impact Factor of his published papers is more than 300 (as per SCOPUS). He has also written more than 25 Books and 45 book chapters in Elsevier, Bentham, Springer and Wiley Publication etc. He has also been granted 3 international patents and 6 Indian patents. Dr. Mishra is recipient of “Distinguished Professor Award” 2019 from DST-NSTMIS, SPAICS, Indore, and M.P. in September 2019. Dr. Mishra has received the “Distinguished Professor Award '' 2021 from Indian Pharmaceutical Association, MP State Branch, Indore. Dr Mishra has received Best Academician Award in the Indian Pharmacy Graduate Association, M.P. State International Conference held on 06th May 2023 at DAVV Auditorium, Indore, India. He is also received one MPCST Project entitled “Dual functional colon- targeted tofacitinib and probiotics loaded microparticles for the treatment of Inflammatory Bowel Disease (2023-24). Dr. Anoop Kumar is an Assistant Professor in the Department of Pharmacology at Delhi Pharmaceutical Sciences & Research University (DPSRU), India. With a distinguished career, he has previously served as an Assistant Professor and Head at the National Institute of Pharmaceutical Education and Research (NIPER), Raebareli, and as Head and Associate Professor at ISF College of Pharmacy, Moga, Punjab. Dr. Kumar has also held research positions at Sun Pharmaceutical Industries Limited and Translational Health Science Institute (THSTI). He earned his Ph.D. from Birla Institute of Technology, Mesra, Ranchi, as a DST INSPIRE Fellow. He is an Associate Editor for Health Sciences Review and Acta Neurologica Scandinavica. His research focuses on drug repurposing, clinical trial meta-analysis, pharmacoeconomics, and pharmacovigilance.