<p>"This book provides a comprehensive explanation of the state-of-the-art methods that are available to predict the effects of chemicals on humans and the environment. … The book fills an obvious need by providing a comprehensive explanation of these prediction methods. It is a practical book that illustrates the use of these techniques in real life scenarios. It will demystify QSARs for those students unsure of the them, and professionals in environmental toxicology and chemistry will find this a useful reference in their everyday working lives."<br /> - International Pest Control, Vol. 47, No. 2, March/April 2005<br /><br /><br /> "The authors and editors have done a fine job in presenting a well balanced view of the early development, current status and future uses of predictive models/(Q)SARs for use in both human health assessments and environmental assessments. … Anyone interested in predictive modelling of mammalian toxicity and environmental effects should consider this book … ."<br /> - BTS Newsletter, Winter 2004, Issue 25<br /><br /> "This choice [of contributors] provides a refreshing outlook on certain topics… we learn what research has been done, what needs most to be done, and why successes have been limited. This is exactly the sort of state-of-the-art description an overview volume should provide."<br /> - Journal of Medicinal Chemistry, Vol. 48, No. 13, 2005</p>

Quantitative Structure-Activity Relationships (QSARs) are increasingly used to predict the harmful effects of chemicals to humans and the environment. The increased use of these methods in a variety of areas (academic, industrial, regulatory) results from a realization that very little toxicological or fate data is available on the vast amount of chemicals to which humans and the environment are exposed.Predicting Chemical Toxicity and Fate provides a comprehensive explanation of the state-of-the-art methods that are available to predict the effects of chemicals on humans and the environment. It describes the use of predictive methods to estimate the physiochemical properties, biological activities, and fate of chemicals. The methods described may be used to predict the properties of drugs before their development, and to predict the environmental effects of chemicals. These methods also reduce the cost of product development and the need for animal testing. This book fills an obvious need by providing a comprehensive explanation of these prediction methods. It is a practical book that illustrates the use of these techniques in real life scenarios. This book will demystify QSARs for those students unsure of them, and professionals in environmental toxicology and chemistry will find this a useful reference in their everyday working lives.
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Quantitative Structure-Activity Relationships are used to predict the effects of chemicals in the environment. Their increased use has been spawned from a realization that there are very few toxicological data for the vast numbers of chemicals released into the environment. This title provides an explanation of the state of the art in these areas.
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Introduction. Methodology. QSARs for Human Health Endpoints. QSARs for Environmental Toxicity and Fate Part. Application.

Produktdetaljer

ISBN
9780415271806
Publisert
2004-05-10
Utgiver
Vendor
CRC Press
Vekt
453 gr
Høyde
254 mm
Bredde
178 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
472

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