Mitochondria and Cancer: From Basic Science to Clinical Applications—Understanding Pathogenesis, Therapy Resistance, and Disease Relapse offers comprehensive perspectives about the role of mitochondria in cancer biology and treatment. This book integrates fundamental scientific knowledge with clinical relevance, presenting recent findings that will engage oncology researchers and provide valuable recommendations for cancer prevention and prognosis. In response to the rising global cancer incidence, this book serves as a comprehensive guide to mitochondrial metabolism in oncology, furthering cancer study and management. It explores a wide range of topics that highlight the multifaceted role of mitochondria in cancer, including tumor microenvironment, cancer stem cells, microbiota, resistance mechanisms, mitochondria-enhancing strategies, and targeted therapies. It includes technical details, research findings, and discussions on the implications of mitochondrial research in cancer treatment and management. Its distinguishing aspects include its comprehensive coverage and diverse perspectives from global experts, providing a well-rounded view of current research.
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1. Mitochondria: Origin, Structure, and Function
2. Mitochondrial Metabolism and Trafficking in Cancer
3. Mitochondrial Genome and Cancer
4. Mitochondrial-nuclear Crosstalk and Its Role in Cancer
5. Mitochondria and Tumor Microenvironment
6. Mitochondria and Cancer Stem Cells
7. Mitochondria, Exosome, Cancer
8. Mitochondria, Microbiota, Cancer
9. MiRNAs and Their Impacts on Cancer Cell’s Mitochondria
10. Mitochondria and Cancer Prevention
11. Mitochondria and Cancer Diagnosis
12. Mitochondrial Metabolism as a Prognostic Biomarker (Mitochondria and Cancer Progression)
13. Mitochondria, Tumor Microenvironment, and Radioresistance
14. Mitochondria and Resistance to Chemotherapy
15. Mitochondria and Resistance to Targeted Therapies
16. Mitochondria and Resistance to Immunotherapy
17. Mitochondria Enhancing Strategies in Cancer
18. Advances in Targeted Anti-mitochondrial Therapies
19. Applying Magnetic Fields to Target Mitochondria
20. what the Artificial Intelligence (AI) Proposes for the Mitochondria Role in Cancer
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Integrates fundamental science with clinical relevance to advance understanding and management of cancer through mitochondrial research
• Delivers an in-depth analysis of how mitochondrial alterations contribute to cancer formation, disease progression, and resistance to conventional and targeted therapies
• Presents comprehensive insights into the dynamic interactions between mitochondria in cancer cells, tumor microenvironment, and microbiota, highlighting their collective influence on cancer progression and therapeutic outcomes
• Combines fundamental scientific knowledge with clinical relevance, covering a wide array of topics from mitochondrial metabolism to innovative therapeutic strategies
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Produktdetaljer
ISBN
9780443405358
Publisert
2026-03-01
Utgiver
Elsevier - Health Sciences Division; Elsevier - Health Sciences Division
Vekt
450 gr
Høyde
276 mm
Bredde
216 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
220