The book elucidates the role of inorganic polyphosphates in eukaryotic cells, from fungi and protozoa to human being. To date, there is plenty of evidence that these anionic biopolymers occurring in the cells of all living organisms, from bacteria to humans, perform numerous regulatory functions. The book describes the evolution of PolyPs, their role in lower eukaryotes and their involvement in various processes in the human organism, as well as its use in biomaterials such as bioactive glass and engineered bone tissue.

The aim of this book is to summarize the data of the past decade on the functional role of inorganic polyphosphates in eukaryotes and discuss their biological role also in context of common human diseases.  The book will provide a modern concept of the functional significance of these biopolymers, useful for researchers in cell biology, biochemistry, molecular biology and biomedicine alike.
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Inorganic polyphosphate multiple function in eukaryotic cell and prospects of these polymers in industry, agriculture and medicine.- The role of inorganic polyphosphate in the stress response and enzyme activities regulation in yeast.- Inorganic polyphosphate in acidocalcisome of protozoa and its role in pathogenesis.- Inorganic polyphosphate in algae.- Inorganic polyphosphates in mycorrhiza.- Inositol polyphosphate and inorganic polyphosphate in cellular functions and human diseases.- PolyP-Ca-polyhydroxybutyrate channels structure and role in eukaryotes.- Inorganic polyphosphates in mitochondria.- Inorganic polyphosphates in brain.- Inorganic polyphosphate in dental tissue development and regeneration.- Inorganic polyphosphate as an inducer of alkaline phosphatase and a modulator of intracellular Ca(2+) level in osteoblasts.- Inorganic polyphosphate and biological apatite nucleation.- Inorganic polyphosphate in blood coagulation.- Inorganic polyphosphate in inflammation.- Prune protein, cancer, Inorganic polyphosphate.- Conclusion:  Evolution of the polyphosphate role in eukaryotes.
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The book elucidates the role of inorganic polyphosphates in eukaryotic cells, from fungi and protozoa to human being. To date, there is plenty of evidence that these anionic biopolymers occurring in the cells of all living organisms, from bacteria to humans, perform numerous regulatory functions. The book describes the evolution of PolyPs, their role in lower eukaryotes and their involvement in various processes in the human organism, as well as its use in biomaterials such as bioactive glass and engineered bone tissue.

The aim of this book is to summarize the data of the past decade on the functional role of inorganic polyphosphates in eukaryotes and discuss their biological role also in context of common human diseases.  The book will provide a modern concept of the functional significance of these biopolymers, useful for researchers in cell biology, biochemistry, molecular biology and biomedicine alike.
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Broadens knowledge on the biological function of PolyPs in Eukaryotes Gives a detailed overview on the function of PolyPs in human diseases Updates on the recent findings in biopolymere research Provides the reader with novel facts on the use of polyphosphates in biomedical engineering
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GPSR Compliance The European Union's (EU) General Product Safety Regulation (GPSR) is a set of rules that requires consumer products to be safe and our obligations to ensure this. If you have any concerns about our products you can contact us on ProductSafety@springernature.com. In case Publisher is established outside the EU, the EU authorized representative is: Springer Nature Customer Service Center GmbH Europaplatz 3 69115 Heidelberg, Germany ProductSafety@springernature.com
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Produktdetaljer

ISBN
9783319410715
Publisert
2016-11-30
Utgiver
Springer International Publishing AG; Springer International Publishing AG
Høyde
235 mm
Bredde
155 mm
Aldersnivå
Research, P, 06
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
243

Om bidragsyterne

Dr. Tatiana Kulakovskaya is Head of Laboratory of Regulation of Biochemical Processes, Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences Moscow.

Dr. Evgeny Pavlov is Assistant Prof at the Department of Basic Science & Craniofacial Biology Faculty , New York University College of Dentistry, NY 

Dr. Elena N. Dedkova, is Associate Researcher at the Departments of Pharmacology University of California - Davis,CA