Edited by renowned protein scientist and bestselling author Roger L. Lundblad, with the assistance of Fiona M. Macdonald of CRC Press, this fifth edition of the Handbook of Biochemistry and Molecular Biology gathers a wealth of information not easily obtained, including information not found on the web.Presented in an organized, concise, and simple-to-use format, this popular reference allows quick access to the most frequently used data. Covering a wide range of topics, from classical biochemistry to proteomics and genomics, it also details the properties of commonly used biochemicals, laboratory solvents, and reagents. An entirely new section on Chemical Biology and Drug Design gathers data on amino acid antagonists, click chemistry, plus glossaries for computational drug design and medicinal chemistry. Each table is exhaustively referenced, giving the user a quick entry point into the primary literature.New tables for this edition: Chromatographic methods and solvents Protein spectroscopy Partial volumes of amino acids Matrix Metalloproteinases Gene Editing Click Chemistry
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A comprehensive compendium of basic biochemical information, the convenient easy-to-use format of this revised edition includes physical and chemical data on proteins, lipids, vitamins, nucleic acids and carbohydrates. New sections will be added on DNA modification, novel protein analysis methods, lipidomics and chemical biology.
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SECTION I: AMINO ACIDS, PEPTIDES, AND PROTEINSProperties of Amino AcidsData on the Naturally Occurring Amino Acids Coefficients of Solubility Equations of Certain Amino Acids in WaterHeat Capacities, Absolute Entropies, and Entropies of Formation of Amino Acids and Related CompoundsHeat of Combustion, Enthalpy, and Free Energy of Formation of Amino Acids and Related Compounds Solubilities of Amino Acids in Water at Various TemperaturesHeats of Solution of Amino Acids in Aqueous Solution at 25°CFree Energies of Solution and Standard Free Energy of Formation of Amino Acids in Aqueous Solution at 25°CFar Ultraviolet Absorption Spectra of Amino AcidsUV Absorption Characteristics of N-Acetyl Methyl Esters of the Aromatic Amino Acids, Cystine, and of N-AcetylcysteineNumerical Values of the Absorbances of the Aromatic Amino Acids in Acid, Neutral, and Alkaline SolutionsHydrophobicities of Amino Acids and ProteinsPartial Volumes of Amino AcidsDeamidation of AsparagineMichael Reactions of ProteinsMolecular Weights of Proteins and Some Other Materials Including Sedimentation, Diffusion, and Frictional Coefficients and Partial Specific VolumesMolar Absorptivity and A1cm 1% Values for Proteins at Selected Wavelengths of the Ultraviolet and Visible RegionTemperature Coefficients of Apparent Partial Specific Volumes of Proteins Expressed in ml/g/deg (dV/dT)Protein pK ValuesIntrinsic Viscosity of ProteinsInfrared Spectra of ProteinsVolume Changes for Some Macromolecule Association ReactionsAssay of Solution Protein Concentration Spectrophotometric Determination of Protein Concentration in the Short-Wavelength UltravioletSECTION II: ENZYMESTurnover of Enzymes in TissuesMolecular Turnover of Cytochromes in AnimalsMatrix MetalloproteinasesProteases in the Interstitial SpaceEnzymes in Synthetic OrganicChemistryTherapeutic EnzymesProtease Inhibitors and Protease Inhibitor CocktailsSECTION III: LIPIDOMICS AND LIPIDOMESEvolution of the Classification and Nomenclature of LipidsA Brief Glossary for LipidomicsA Comprehensive Classification System for LipidsProperties of Fatty Acids and Their Methyl EstersDensities, Specific Volumes, and Temperature Coefficients of Fatty Acids from C8 to C12Composition and Properties of Common Oils and FatsSpectral Properties of Fatty AcidsIR Active Bands of Phosphatidylethanolamines (PE)Concentration of Some Fatty Acids in Human Blood, Blood Plasma or Blood SerumSome Unusual Fatty Acid StructuresSECTION IV: VITAMINS AND COE NZYMESProperties of VitaminsBiological Characteristics of VitaminsVitamersVitamin Names DiscardedSECTION V: NUCLEIC ACIDSSome Definitions for Nucleic Acids UV Spectral Characteristics and Acidic Dissociation Constants of 280 Alkyl Bases, Nucleosides, and NucleotidesUltraviolet Absorbance of Oligonucleotides Containing 2′-O-Methylpentose ResiduesSpectrophotometric Constants of RibonucleotidesPurines, Pyrimidines, Nucleosides, and Nucleotides: Physical Constants and Spectral PropertiesChemical Modification of Nucleic AcidsPolymerase Chain ReactionGene EditingSECTION VI: GLYCOSCIENCENomenclature of CarbohydratesChemical Modification of CarbohydratesSome Properties of GlycosaminoglycansSugar MimeticsIntrinsic Viscosity of PolysaccharidesSECTION VII: CHEMICAL BIOLOGY AND DRUG DESIGNUnnatural Amino Acids for Incorporation into ProteinsStructures and Symbols for Synthetic Amino Acids Incorporated into Synthetic PolypeptidesProperties of the α-Keto Acid Analogs of Amino Acidsα,β-Unsaturated Amino AcidsAmino Acid AntagonistsParticle DiameterWeights of Cells and Cell ConstituentsClick ChemistryA Listing of Log P Values, Water Solubility, and Molecular Weight for Some Selected ChemicalsSECTION VIII: PHYSICAL AND CHEMICAL DATAIUBMB-IUPAC Joint Commission on Biochemical Nomenclature (JCBN) Recommendations for Nomenclature and Tables in Biochemical ThermodynamicsStandard Transformed Gibbs Energies of Formation for Biochemical ReactantsEnthalpy, Entropy, and Free Energy Values for Biochemical Redox ReactionsOxidation-Reduction Potentials, Absorbance Bands, and Molar Absorbance of Compounds Used in Biochemical StudiesCalorimetric ΔH Values Accompanying Conformational Changes of Macromolecules in SolutionFree Energies of Hydrolysis and DecarboxylationDeci-Normal Solutions of Oxidation and Reduction ReagentsGuidelines for Potentiometric Measurements in Suspensions Part A — The Suspension EffectIonization Constants of Acids and BasesGuidelines for NMR Measurements for Determination of High and Low pKa ValuesMeasurement and Interpretation of Electrokinetic PhenomenaMeasurement of pH Definition, Standards, and ProceduresGeneral Comments on BuffersList of BuffersBronsted AciditiesBuffer SolutionsAmine Buffers Useful for Biological ResearchPreparation of Buffers for Use in Enzyme StudiesIndicators for Volumetric Work and pH DeterminationsAcid and Base IndicatorsSpecific Gravity of LiquidsProperties of Some SolventsChemicals Commonly Used in Biochemistry and Molecular Biology and their PropertiesCommon Detergents Used in Biochemical ResearchSome Properties of Detergents and Surfactants Used in Biochemistry and Molecular BiologySome Biological Stains and DyesMordant DyesMetal Chelating AgentsMetallomics: Guidelines for Terminology and Critical Evaluation of Analytical Chemistry Approaches (IUPAC Technical Report)WaterGeneral Information on SpectroscopyPlasticsChemical and Physical Properties of Various Commercial PlasticsChemical Resistance of PlasticsGeneric Source-Based Nomenclature for PolymersDefinitions of Terms Relating to Reactions of Polymers and to Functional Polymeric MaterialsDefinitions of Terms Related to Polymer Blends, Composites, and Multiphase Polymeric MaterialsTerminology for Biorelated Polymers and Applications (IUPAC Recommendations 2012)Intrinsic Viscosity of Poly(ethylene glycol)International Union of Pure and Applied ChemistryOrganic Name Reactions Useful in Biochemistry and Molecular BiologyBrief Guide to the Nomenclature of Inorganic Chemistry Properties of Fluorescent Probes Commonly Used for Membrane StudiesChromatographyBlotting TechnologiesOxidation of ThiolsPartial Volumes for Some Selected CompoundsAppendix: Abbreviations and Acronyms
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Produktdetaljer

ISBN
9781138033092
Publisert
2018-06-25
Utgave
5. utgave
Utgiver
Vendor
CRC Press
Vekt
2696 gr
Høyde
280 mm
Bredde
210 mm
Aldersnivå
U, G, 05, 01
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
1018

Om bidragsyterne

Roger L. Lundblad, Ph.D. Roger L. Lundblad is a native of San Francisco, California. He received his undergraduate education at Pacific Lutheran University and his PhD degree in biochemistry at the University of Washington. After postdoctoral work in the laboratories of Stanford Moore and William Stein at the Rockefeller University, he joined the faculty of the University of North Carolina at Chapel Hill. He joined the Hyland Division of Baxter Healthcare in 1990. Currently Dr. Lundblad is an independent consultant and writer in biotechnology in Chapel Hill, North Carolina. He is an adjunct Professor of Pathology at the University of North Carolina at Chapel Hill and Editor-in-Chief of the Internet Journal of Genomics and Proteomics. Fiona M. Macdonald, Ph.D., F.R.S.C. Fiona M. Macdonald received her BSc in chemistry from Durham University, UK. She obtained her PhD in inorganic biochemistry at Birkbeck College, University of London, studying under Peter Sadler. Having spent most of her career in scientific publishing, she is now at Taylor and Francis and is involved in developing chemical information products.