For all introductory genetics courses
Informed by many years of genetics teaching and research expertise, authors Mark Sanders and John Bowman use an integrated approach that helps contextualise three core challenges of learning genetics: solving problems, understanding evolution, and understanding the connection between traditional genetics models and more modern approaches.

1. 1 The Molecular Basis of Heredity, Variation, and Evolution  
2. 2 Transmission Genetics  
3. 3 Cell Division and Chromosome Heredity  
4. 4 Inheritance Patterns of Single Genes and Gene Interaction  
5. 5 Genetic Linkage and Mapping in Eukaryotes  
6. 6 Genetic Analysis and Mapping in Bacteria and Bacteriophages  
7. 7 DNA Structure and Replication  
8. 8 Molecular Biology of Transcription and RNA Processing 
9. 9 The Molecular Biology of Translation  
10. 10 The Integration of Genetic Approaches: Understanding Sickle Cell Disease 
11. 11 Chromosome Structure  
12. 12   Gene Mutation, DNA Repair, and Homologous Recombination  
13. 13   Chromosome Aberrations and Transposition  
14. 14   Regulation of Gene Expression in Bacteria and Bacteriophage  
15. 15 Regulation of Gene Expression in Eukaryotes  
16. 16 Analysis of Gene Function via Forward Genetics and Reverse Genetics  
17. 17 Recombinant DNA Technology and Its Applications  
18. 18 Genomics: Genetics from a Whole-Genome Perspective  
19. 19   Organelle Inheritance and the Evolution of Organelle Genomes  
20. 20 Developmental Genetics  
21. 21   Genetic Analysis of Quantitative Traits  
22. 22 Population Genetics and Evolution at the Population, Species, and Molecular Levels  

• Genetic Analysis worked examples guide students using a consistent 3-step approach of Evaluate, Deduce, and then Solve problems.
• Break It Down prompts in worked examples start students in formulating an approach to solving a problem by breaking down essential information.

• Case Studies are real-world examples that highlight chapter concepts and show practical applications of genetics.
• 9 Foundation Figures combine visuals and words to help students grasp pivotal genetics concepts in a concise, easy-to-follow format.
• An integrated evolutionary perspective helps students keep sight of important evolutionary principles while learning core concepts.

Develop Problem Solving Skills

• NEW! Component has been added to each Genetic Analysis worked example to help students get started with formulating an approach to solving a problem.

Engage Students in the Process of Science and Genetic Discoveries

• NEW! Integrated coverage of genomics throughout. Genomic investigations are rapidly expanding and changing what we know about genetics. Coverage of important techniques and findings are integrated throughout the text, such as a new discussion of the impact of lateral gene transfer on bacterial genomes in Chapter 6; a new Experimental Insight of cancer genomics in Chapter 12; discussions of new genome methods and analyses in Chapter 18; and updated coverage of the human genome, including data on interaction with Neandertals and Denisovans in Chapter 22.
• NEW! Revised and expanded coverage of epigenetics in Chapters 11 and 15. Coverage in Chapter 15 has been substantially rewritten to expand the discussion of epigenetics, including new information on the histone code and chromatin states, and on epigenetic readers, writers, and erasers.
• NEW! Expanded coverage of archaea molecular biology. Recent advancements in understanding the genetics and molecular biology of archaea are described where appropriate. These recent findings allow insightful comparisons to the genetics of bacteria and eukaryotes, particularly in relation to molecular genetic processes and to evolution. New archaea discussions and descriptions appear in Chapters 7, 8, 9, 11, 12, and 14.
• NEW! Enhanced coverage of molecular evolution. The texts focus on evolution in genetics now includes more coverage of molecular evolution integrated into appropriate chapters. Chapters 7, 8 and 9 have expanded discussions of the evolution of the processes of replication, transcription, and translation. Chapter 11 discusses the evolution of histone proteins in archaea and eukaryotes. Chapter 14 describes evolutionary comparisons of regulatory mechanisms in archaea and bacteria. Chapter 15 contains expanded coverage of the evolution of regulatory functions. Chapter 22 contains new discussions of evolution at the population, species, and molecular levels.
• Unique Chapter 10: The Integration of Genetic Approaches integrates transmission genetics, molecular analysis, molecular techniques, and evolution in an exploration of human sickle cell disease.

Help Students Distill the Most Important Take Home Lessons

• NEW! Foundation Figures combine visuals and words to help students grasp pivotal genetics concepts in a concise, easy-to-follow format. Four new Foundation Figures have been added to this edition to help students understand DNA Replication (Chapter 7), Bacterial Transcription (Chapter 8), Bacterial Translation Elongation (Chapter 9) and the Molecular Model of Meiotic Recombination (Chapter 12).