Emerging Strategies in Cancer Metabolism: Role of Gut Microbiota, Reactive Oxygen Species, and Short Chain Fatty Acids offers a revolutionary investigation of the complicated relationships between cancer metabolism and three crucial factors: the gut microbiota, reactive oxygen species (ROS), and the dysregulation of the short chain fatty acid (SCF) complex. This book adopts a thorough and interdisciplinary approach to untangle the intricate interactions between these components, providing fresh perspectives that fundamentally alters the understanding of cancer biology and therapy. In 14 chapters. Emerging Strategies in Cancer Metabolism: Role of Gut Microbiota, Reactive Oxygen Species, and Short Chain Fatty Acids provides a thorough investigation of the metabolic changes that occur inside cancer cells, illuminating how these changes promote tumour survival and progression, from introduction to future aspects. Researchers in cancer research, and gut microbiology will find this an essential reference.
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1. Introduction to Gut Microbiota in Cancer Metabolism 2. Cancer Metabolic Rewiring of Reactive Oxygen Species 3. Emerging strategies in Cancer metabolism: Role of Gut microbiota, reactive oxygen species, and short chain fatty acids 4. Exploring the Link Between Gut Microbiome and Cancer: Metabolic Implications and Therapeutic Avenue 5. Oxidative Stress and Cancer Metabolism: From Pathogenesis to Therapeutic Opportunities 6. Targeting ROS Signaling Pathways for Cancer Metabolic Reprogramming 7. SCF Complex: Master Regulator of Metabolic Adaptations in Cancer Cells 8. Manipulating gut microbial metabolites for cancer therapy: A Metabolism-centric approach 9. Metabolic Crossroads: Integrating ROS, SCF and Gut Microbiota in Cancer 10. Therapeutic Advances: Modulating Gut Microbiota, ROS, and SCF Pathways in Cancer Treatment 11. Precision Medicine in Cancer Metabolism: Personalized Approaches Exploiting Metabolic Vulnerabilities 12. Novel Biomarkers and Therapeutic Targets: Harnessing Metabolic Insights for Improved Cancer Management 13. Future aspects: Novel Strategies in Cancer Metabolism Research and Clinical Interventions 14. Novel approach in Bridging the Gap between Cancer Biology and Metabolism 15. Implementing Gut Microbiota, ROS, and SCF Modulation in Cancer Care: Research into Practice
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Provides a thorough grasp of the conceptual basis and current state of probiotics and metabolites in cancer diagnosis, prognosis, and treatment
Creates new opportunities for focused therapies and patient-specific therapy plans by exploring the roles of the gut microbiota, ROS, and SCF dysregulation in cancer metabolism Discusses in-vitro, ex-vivo, and animal models used to examine the effects of probiotics and their metabolites in cancer care Focuses on cutting-edge research on probiotics and their byproducts treatments in oncogene downregulation, autophagy induction, kinase inhibition, tumour suppressor reactivation, and metastasis prevention
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Produktdetaljer

ISBN
9780443334597
Publisert
2025-12-01
Utgiver
Elsevier Science Publishing Co Inc; Academic Press Inc
Høyde
235 mm
Bredde
191 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
320

Om bidragsyterne

Dr. Mishra is working as Professor in Amity Institute of Pharmacy, Gwalior since July 2019. He has around twenty-two years of teaching and research experience. He has more than 140 publications of International and National repute in recent concepts of novel drug delivery systems, localized drug delivery, targeted and controlled drug delivery of nanocarriers/ microparticles for the treatment of breast, colon cancer, and neurodegenerative disorders. Dr. Mishra more than 4100 citations with h- index 36. The total cumulative Impact Factor of his published papers is more than 300 (as per SCOPUS). He has also written more than 25 Books and 45 book chapters in Elsevier, Bentham, Springer and Wiley Publication etc. He has also been granted 3 international patents and 6 Indian patents. Dr. Mishra is recipient of “Distinguished Professor Award” 2019 from DST-NSTMIS, SPAICS, Indore, and M.P. in September 2019. Dr. Mishra has received the “Distinguished Professor Award '' 2021 from Indian Pharmaceutical Association, MP State Branch, Indore. Dr Mishra has received Best Academician Award in the Indian Pharmacy Graduate Association, M.P. State International Conference held on 06th May 2023 at DAVV Auditorium, Indore, India. He is also received one MPCST Project entitled “Dual functional colon- targeted tofacitinib and probiotics loaded microparticles for the treatment of Inflammatory Bowel Disease (2023-24). Dr. Kuttiappan Anitha is working as Assistant Professor in School of Pharmacy and Technology Management (SPTM), SVKM's Narsee Monjee Institute of Management Studies (NMIMS) Deemed-to-University, Shirpur. She has broad teaching and research experience. Dr. Anitha is recipient of “Excellence in Academic Award” 2022 from International School of Technology and Sciences Affiliated from Govt. of India. She has guided more than 45 M.Pharm students and more than 10 batches of UG Projects. She has more than 30 publications in both national and international journals. Her area of expertise includes Immunooncology, endocrine areas, Gut Microbiota, infectious Diseases. She has also written several books and many book chapters. She has organized Conferences/seminars at university levels. Prof. Goutam Rath is currently serving as Professor in the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, India. A leading researcher in nanotechnology-based platform technologies for site-specific drug and bioactive delivery, Prof. Rath has earned global recognition for his scientific contributions. He has been listed among the world’s top 2% scientists by Stanford University (USA) for four consecutive years (2019–2024). In 2018, he was named one of the Top 10 Scientists of India by Career 360 and was awarded for best GMP practices by the USFDA. Prof. Rath has successfully led numerous national research projects with cumulative funding exceeding ₹22.2 crores from prestigious agencies like NITI Aayog, DBT, DST, AICTE, UGC, and ICMR. He has authored over 250 peer-reviewed publications with a cumulative impact factor of approximately 1080, an h-index of 59, and over 10,800 citations. Additionally, he has contributed to four textbooks, 20 book chapters, and over 60 scientific presentations. His innovative work is protected by 21 patents, six of which have been commercially transferred, generating revenues of ₹37 lakhs. He currently supervises 85 M.Pharm and 10 Ph.D. scholars, and serves on multiple national expert panels in biotechnology and nanomedicine.