/

Dynamic Bacterial Genome

Mullany, Peter
Heftet / 2010 / Engelsk

Produktdetaljer

ISBN
9780521129619
Publisert
2010-02-04
Utgiver
Vendor
Cambridge University Press
Vekt
650 gr
Høyde
229 mm
Bredde
152 mm
Dybde
25 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
444

Redaktør
Mullany, Peter

Om bidragsyterne

Peter Mullany is a Reader in Molecular Microbiology at University College London. His main research interests are the molecular biology and molecular ecology of conjugative transposons. He has been at the forefront of this work for the past 10 years and has pioneered the genetic analysis of the important human pathogen Clostridium difficile.

Dynamic Bacterial Genome

Mullany, Peter
Heftet / 2010 / Engelsk
Mullany, Peter
Heftet / 2010 / Engelsk
Nettpris:
879,-
Levering 7-20 dager
Sjekk lagerstatus i butikk

Review of the hardback: 'The book is well structured, thorough and thoughtful, and a rich source of information about the amazing dynamics of bacterial genomes.' Microbiology Today

This book provides an in-depth analysis of the mechanisms and biological consequences of genome rearrangements in bacteria. Genome rearrangements are a result of the actions of discrete genetic elements such as conjugative transposons, plasmids, phage, and non-conjugative transposons. Bacteria also contain systems to mediate genetic rearrangements such as the general recombination pathway and specialized endogenous recombination mechanisms. The biological effects of these rearrangements are far-reaching and impact on bacterial virulence, antibiotic resistance and the ability of bacteria to avoid the attentions of the host immune system (e.g. antigenic variation). These rearrangements also provide the raw material on which natural selection can act. Each chapter examines the mechanisms involved in genome rearrangements and the direct biological consequences of these events. This book is written by leading research workers and is an invaluable resource for graduate students and researchers in this field.
Les mer
This book is concerned with the mechanisms underlying recombination in bacterial DNA.
Part I. Basic Mechanisms of Genome Rearrangement in Bacteria: 1. Mechanisms of homologous recombination in bacteria Marie-Agnès Petit; 2. Introduction to site-specific recombination Makkuni Jayaram and Ian Grainge; 3. Site-specific recombination by the serine recombinases Sally J. Rowland and W. Marshall Stark; 4. Mobile introns and retroelements in bacteria Steve Zimmerly; Part II. Horizontal Gene Transfer and Genome Plasticity: 5. The F-Plasmid, a paradigm for bacterial conjugation Michael J. Gubbins, William R. Will and Laura S. Frost; 6. Molecular aspects of movement of conjugative transposons Adam P. Roberts and Peter Mullany; 7. Competence for genetic transformation Irena Draskovic and David Dubnau; Part III. Biological Consequences of the Mobile Genome: 8. Phase variation and antigenic variation Richard Villemur and Eric Déziel; 9. Pathogenicity islands Bianca Hochhut and Jörg Hacker; 10. Biological consequences for bacteria of homologous recombination Diarmaid Hughes and Tobias Norström; 11. Horizontal gene transfer and bacterial genomic legacies James R. Brown.
Les mer
This book is concerned with the mechanisms underlying recombination in bacterial DNA.

Relaterte produkter

Review of the hardback: 'The book is well structured, thorough and thoughtful, and a rich source of information about the amazing dynamics of bacterial genomes.' Microbiology Today

This book provides an in-depth analysis of the mechanisms and biological consequences of genome rearrangements in bacteria. Genome rearrangements are a result of the actions of discrete genetic elements such as conjugative transposons, plasmids, phage, and non-conjugative transposons. Bacteria also contain systems to mediate genetic rearrangements such as the general recombination pathway and specialized endogenous recombination mechanisms. The biological effects of these rearrangements are far-reaching and impact on bacterial virulence, antibiotic resistance and the ability of bacteria to avoid the attentions of the host immune system (e.g. antigenic variation). These rearrangements also provide the raw material on which natural selection can act. Each chapter examines the mechanisms involved in genome rearrangements and the direct biological consequences of these events. This book is written by leading research workers and is an invaluable resource for graduate students and researchers in this field.
Les mer
This book is concerned with the mechanisms underlying recombination in bacterial DNA.
Part I. Basic Mechanisms of Genome Rearrangement in Bacteria: 1. Mechanisms of homologous recombination in bacteria Marie-Agnès Petit; 2. Introduction to site-specific recombination Makkuni Jayaram and Ian Grainge; 3. Site-specific recombination by the serine recombinases Sally J. Rowland and W. Marshall Stark; 4. Mobile introns and retroelements in bacteria Steve Zimmerly; Part II. Horizontal Gene Transfer and Genome Plasticity: 5. The F-Plasmid, a paradigm for bacterial conjugation Michael J. Gubbins, William R. Will and Laura S. Frost; 6. Molecular aspects of movement of conjugative transposons Adam P. Roberts and Peter Mullany; 7. Competence for genetic transformation Irena Draskovic and David Dubnau; Part III. Biological Consequences of the Mobile Genome: 8. Phase variation and antigenic variation Richard Villemur and Eric Déziel; 9. Pathogenicity islands Bianca Hochhut and Jörg Hacker; 10. Biological consequences for bacteria of homologous recombination Diarmaid Hughes and Tobias Norström; 11. Horizontal gene transfer and bacterial genomic legacies James R. Brown.
Les mer
This book is concerned with the mechanisms underlying recombination in bacterial DNA.

Produktdetaljer

ISBN
9780521129619
Publisert
2010-02-04
Utgiver
Vendor
Cambridge University Press
Vekt
650 gr
Høyde
229 mm
Bredde
152 mm
Dybde
25 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
444

Redaktør
Mullany, Peter

Om bidragsyterne

Peter Mullany is a Reader in Molecular Microbiology at University College London. His main research interests are the molecular biology and molecular ecology of conjugative transposons. He has been at the forefront of this work for the past 10 years and has pioneered the genetic analysis of the important human pathogen Clostridium difficile.

Relaterte produkter