Variety of bacteria are present in our environment but only a few of these bacteria causes diseases in their hosts including humans. These bacteria face different stresses in the environment as well as inside the host and adapt number of strategies for their survival. In 5 parts Bacterial Survival in the Hostile Environment covers all tactics and strategies adopted by bacteria for their survival under stressed conditions and will be focused on mechanistic insights of pathogenic adaptations to host environments (acidic environment, microaerobic conditions, immune system stress, metal stress etc., modulation of host pathways by pathogens for survival, dormancy, drug tolerance and resistance, proteins for stress survival). The content also includes different adaptation mechanisms of extremophiles to extreme environment, provides a complete and globally available advance knowledge related to bacterial survival from different perspectives and reviews the knowledge gaps and future prospects in the field of microbial adaptation for sustainable development of in the field of infection biology and pharmaceutics.
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Chapter 1. Mycobacterium tuberculosis adaptation to host environment Chapter 2. Modulation of host pathways by Mycobacterium tuberculosis for survival Chapter 3. Signaling nucleotides in bacteria Chapter 4. The fish immune armaments in response to pathogen invasion—a tour inside the macrophages Chapter 5. Essential proteins for the survival of bacteria in hostile environment Chapter 6. Kinases and phosphatases in bacterial survival in hostile environment Chapter 7. Antimicrobial resistance—a serious global threat Chapter 8. Combination of virulence and antibiotic resistance: a successful bacterial strategy to survive under hostile environments Chapter 9. Mechanisms of biofilm-based antibiotic resistance and tolerance in Mycobacterium tuberculosis Chapter 10. Biofilms: cities of microorganisms Chapter 11. Biofilm: a coordinated response of bacteria against stresses Chapter 12. The bacterial communication system and its interference as an antivirulence strategy Chapter 13. Microbial adaptations in extreme environmental conditions Chapter 14. Adaptation strategies of piezophilic microbes Chapter 15. Survival and adaptation strategies of microorganisms in the extreme radiation Chapter 16. Adaptation strategies of thermophilic microbes
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Addresses the gap in the critical pathogen biology and pharmaceutical issues with the detail information of the inconspicuous microbial survival mechanisms
Provides in depth knowledge about pathogen biology and microbial adaptations, microbe-host interactions, impact of pathogens on host physiology, virulent factors produced by pathogens and pharmaceutical applications, mechanism of pathogenic virulent factors Covers all tactics and strategies adopted by bacteria for their survival under stressed conditions Focuses on mechanistic insights of pathogenic adaptations to host Includes different adaptation mechanisms of extremophiles to extreme environment
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Produktdetaljer

ISBN
9780323918060
Publisert
2022-09-29
Utgiver
Vendor
Academic Press Inc
Vekt
570 gr
Høyde
235 mm
Bredde
191 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet

Redaktør

Om bidragsyterne

Dr. Ashutosh Kumar is an active researcher and scientific writer in his field for over 14 years and presently working at Department of Microbiology, Tripura University (A Central University), Suryamaninagar, Agartala, Tripura, India. He received MSc and PhD degree in Biotechnology from University of Hyderabad, India. He did his postdoctoral research at TIFR-National Centre for Biological Sciences Bangalore, Indian Institute of Technology Delhi and Jamia Hamdard, New Delhi, India. He also worked as a Visiting Research Scientist at Robert Koch Institute Berlin, Germany. He has made significant contributions to the study of virulence mechanisms and strategies of survival, adaptation, and persistence of Mycobacterium tuberculosis. He was involved in identification of an enzyme from M. tuberculosis that promote biofilm formation and drugs that enhanced the potency of two current anti-tuberculosis antibiotics. He received many scholarships, awards, and fellowship during his education. He has many publications in international journals and books. Dr. Tenguria is an active researcher and currently working as Project Scientist in Cedars-Sinai Medical Center, Los Angeles, CA USA. He has been actively involved in research and training of graduate and undergraduate students. He received his MSc in Life Sciences from University of Rajasthan, Jaipur and PhD in Biotechnology from University of Hyderabad, Hyderabad, India. He received his postdoctoral training from Purdue University, Indiana, USA and Cedars-Sinai Medical Center (UCLA), Los Angeles, California, USA. Currently, he is working in the area of molecular innate immunity to unravel molecular signaling mechanics for sensing danger (infectious pathogens) signals through cytosolic receptors of the innate immune system of human and mouse hosts. With his doctoral and postdoctoral fellowships and research in the area of host-microbe interactions, bacterial survival and pathogenesis, he made seminal contributions by publishing in international Jr (Cell Host-Microbe, Nature Commun, Frontiers).