Developments of antifungal agents have declined as compared to other antibiotics that have displayed a potent development with time. There is an urgent need for both prophylactic and therapeutic treatments worldwide to control the severity of infections caused by Candida. Anticandidal Therapeutics: Discovery and Development provides the readers with a compiled knowledge of the fungal human infection Candida and the development of anticandidal drugs. Anticandidal Therapeutics helps researchers form the basis for the discovery and development of novel anticandidal therapies. In 14 chapters this book provides collective information on anticandidal agents and their discovery and development with respect to major drug transporter families, different stages of anticandidal agent development, recent trends and progress in antifungal translational research, clinical studies status of anticandidal therapeutic agents, and drug repurposing for development of novel anticandidal agents.
Les mer
1. History of infection 2. Brief introduction on infection 3. Fungal diseases and antifungal drugs 4. Multidrug transporters of fungal pathogen Candida 5. Essential anticandidal targets 6. Stages of anticandidal agent development 7. Recent trends and progress in antifungal translational research 8. Clinical status of anticandidal therapeutic agents 9. Drug repurposing for development of effective anticandidals 10. Commercial aspects of drug development 11. Challenges and future prospects
Les mer
Provides a previous background on fungal infection in humans and animals in addition to background on fungal resistance to drugs
Highlights the mechanistic actions of some therapeutic agents against Candida
Focuses on anticandidal agents rather than general antifungal agents
Discusses the stage of development of new antifungal drugs, the repositioning of drugs, and how this could help in treatment
Les mer
Produktdetaljer
ISBN
9780443187445
Publisert
2023-01-23
Utgiver
Vendor
Academic Press Inc
Vekt
450 gr
Høyde
235 mm
Bredde
191 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
196
Forfatter