This book constitutes the refereed proceedings of the 10th International Conference on Evolutionary Multi-Criterion Optimization, EMO 2019 held in East Lansing, MI, USA, in March 2019.The 59 revised full papers were carefully reviewed and selected from 76 submissions. The papers are divided into 8 categories, each representing a key area of current interest in the EMO field today. They include theoretical developments, algorithmic developments, issues in many-objective optimization, performance metrics, knowledge extraction and surrogate-based EMO, multi-objective combinatorial problem solving, MCDM and interactive EMO methods, and applications.