A comprehensive overview of schizophrenia and its treatment from a variety of approaches. The book presents a balanced look at the most influential theroetical perspectives based on empirical research, clinical descriptions, and narrative histories.

Preface Section I: The development, Evolution, Epidemiology, and Subsyndromes of Schizophrenia Chapter 1. History of the Concept of Schizophrenia The Premodern Period The Nineteenth Century Origins of the Concept of Schizophrenia Emil Kraepelin Adolph Meyer Eugen Bleuler Summary Chapter 2. Evolving Diagnostic Criteria Diagnosing Schizophrenia DSM-I DSM-II Problems with Diagnostic Reliability European Diagnostic Efforts Research Definitions DSM-III DSM-IV Reliability and Validity Summary Chapter 3. Epidemiology, Course, and Outcome Prevalence and Incidence Phases of Schizophrenia Long-Term Outcome Positive and Negative Symptoms Symptom and Premorbid Predictors of Outcome Schizophrenia and Comorbid Substance Use The Role of Culture in Outcome: The WHO International Pilot Study of Schizophrenia (IPSS) Summary Chapter 4. Language, Thought, and Syndromes of Schizophrenia Delusions? Categories of Symptoms Summary Section II. Integrative Models and Level of Analysis Chapter 5. Vulnerability-Stress Models A Two-Hit Biological Model of Diathesis-Stress Vulnerability Stress Summary Chapter 6. Epistemology, General Systems Theory, and Schizophrenia General Systems Theory Summary Section III. Biological Perspectives Chapter 7. Genetics and Schizophrenia Genetic Models The Nature of Genetic Influence Concordance Research Basic Genetic Research Summary Chapter 8. Neurobiological Models and Research Studies of Specific Brain Abnormalities Neurobiological Modular Systems and Clusters of Schizophrenia Symptoms Cognitive Dysmetria Modular Disjunction Dysfunctions in Interrelated Systems and Symptom Clusters Summary Chapter 9. Antipsychotic Medications and Neurochemical Theories Efficacy of Typical Antipsychotics The Dopamine Hypothesis Atypical Antipsychotics The Hyperdopaminergic Hypothesis and Glutamate Schizophrenia: A Neurotransmitter Imbalance Syndrome? Summary Section IV. Cognitive-Behavioral, Neurocognitive, and Neurodevelopmental Research Chapter 10. Neurocognitive and Neurodevelopmental Research Neurocognitive Indicators of Vulnerability Neurodevelopmental Precursors to Clinical Symptoms Therapies for Neurocognitive Deficits Summary Chapter 11. Cognitive-Behavioral Approaches and Therapies Applied Behavioral Analysis The Cognitive-Behavioral Approach Broad-Spectrum Cognitive Therapy Symptom-Focused Cognitive Interventions Social Cognition and Schizophrenia Cognitive-Behavioral Intervention Programs Tailored to Symptom Phase Personal Therapy (PT): A Disorder-Relevant Therapy Summary Section V. Psychodynamic, Phenomenological, and Family-Based Theories Chapter 12. Psychodynamic Theories: The Role of Early Experience Background Sullivan’s Interpersonal Theory The Kleinian School Margaret Mahler Object Relations and Delusions Robbins Hierarchical Systems/Psychoanalytical Model Contemporary Psychodynamic Therapies Summary Chapter 13. Phenomenology and Schizophrenia Delusions and the Relationship to the Outer World The Process of Delusion Formation Schizophrenic and Nonschizophrenic Delusions Daseinanalysis Summary Chapter 14. Schizophrenia and the Family Murray Bowen and the Washington Group Theodore Lidz and the Yale Group Y.O. Alanen and Finnish Family Research The Palo Alto GroupJackson, Bateson, Haley, Weakland, Satir, and Watzlawick Experimental Family StudiesMishler and Waxler The Rochester Research GroupWynne and Singer Summary Section VI. Psychodynamic, Phenomenological,