_TRP Channels as Therapeutic Targets: From Basic Science to Clinical
Use_ is authored by experts across academia and industry, providing
readers with a complete picture of the therapeutic potential and
challenges associated with using TRP channels as drug targets.
This book offers a unique clinical approach by covering compounds that
target TRP channels in pre-clinical and clinical phases, also offering
a discussion of TRP channels as biomarkers.
An entire section is devoted to the novel and innovative uses of these
channels across a variety of diseases, offering strategies that can be
used to overcome the adverse effects of first generation TRPV1
antagonists.
Intended for all researchers and clinicians working toward the
development of successful drugs targeting TRP channels, this book is
an essential resource chocked full of the latest clinical data and
findings.
* Contains comprehensive coverage of TRP channels as therapeutic
targets, from emerging clinical indications to completed clinical
trials
* Discusses TRP channels as validated targets, ranging from obesity
and diabetes through cancer and respiratory disorders, kidney
diseases, hypertension, neurodegenerative disorders, and more
* Provides critical analysis of the complications and side effects
that have surfaced during clinical trials, offering evidence-based
suggestions for overcoming them
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Produktdetaljer
ISBN
9780124200241
Publisert
2015
Utgiver
Vendor
Academic Press Inc
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
536
Forfatter