Glucose-Lowering and Metabolic Effects of SGLT2 Inhibitors Renoprotective Effects of SGLT2 Inhibitors SGLT2 Inhibitors in Type 2 Diabetes Mellitus SGLT2 Inhibitors in Heart Failure with Reduced Ejection Fraction: A Paradigm Shift Toward Dual Cardio-Renal Protection SGLT2 Inhibitors and Heart Failure with Preserved Ejection Fraction SGLT2 Inhibitors in Heart Failure: Early Initiation to Achieve Rapid Clinical Benefits Sodium-Glucose Cotransporter-2 Inhibitors: Impact on Atherosclerosis and Atherosclerotic Cardiovascular Disease Events SGLT2 Inhibitors and Peripheral Vascular Events: A Review of the Literature Sodium-glucose Cotransporter 2 Inhibitors and Nonalcoholic Fatty Liver Disease SGLT2 Inhibitors and Safety in Older Patients Sodium Glucose Cotransporter 2 Inhibitors, Amputation Risk, and Fracture Risk