Acknowledgments vii

Introduction ix

Clinical trials and organizations: abbreviations and acronyms xv

1 Classification, diagnosis and presentation 1

2 Diabetes emergencies 25

3 Infections and the diabetic foot 49

4 Eyes and kidneys 77

5 Neuropathy, musculoskeletal and skin 115

6 Diabetes and the cardiovascular system 141

7 Type 1 diabetes: glycaemic control 171

8 Type 1 diabetes: technology and transplants 197

9 Type 2 diabetes: weight loss, exercise and other ‘lifestyle’ interventions 217

10 Type 2 diabetes: glycaemic control 241

11 Hypertension 315

12 Lipids 359

13 Clinical aspects of the metabolic syndrome 387

14 Youth and emerging adulthood; old age 401

15 Psychological aspects of diabetes 425

Index 439

The fourth edition of this popular textbook has been fully updated and completely rewritten to present important recent evidence, and to translate it into practical guidance for new and more effective approaches to the management of diabetes. A concise and comprehensive guide to Type 1 and Type 2 diabetes in primary and secondary care, it emphasises the importance of team-based management and integrated care, and focuses on the extended reach of all types of diabetes. The book is based on results of important historical and modern clinical trials, and helps practitioners place current guidelines in clinical context. It focuses on difficult and contentious areas of management, especially where there are rapidly moving new therapies. Lifestyle approaches in Type 2 diabetes and new technology in the management of Type 1 diabetes are discussed in detail, and there are completely new chapters on diabetes in youth and old age, and cardiovascular disease. References are fully updated with PubMed PMID access numbers, and throughout Practice Points have been added to summarise critical matters of management and safety.

Foundation and specialist trainees in general and acute medicine, diabetes and endocrinology, as well as specialist diabetes nurses will find all they need here for hospital practice. In the community, general practitioners with an interest in diabetes, nurse practitioners and pharmacists will find it an invaluable reference. Its extensive scope and referencing will help all clinicians studying for postgraduate diplomas and examinations.