This book presents original case studies performed on dedicated PET-CT devices and showcases common and uncommon cancers and the latest PET-CT applications for neurological, pediatric, and cardiovascular disorders. This authoritative book, now in its Second Edition, presents correlative three-dimensional cross-sectional PET and CT images that highlight pathological findings. Each case example is accompanied by a concise explanation of the patient history and interpretation of the PET-CT study. "Pearls and pitfalls" and insightful discussions are included to assist in the understanding of pathology, diagnosis, and imaging approaches. The book also discusses pathophysiology and technical artifacts and summarizes the advantages and limitations of using this technology in the clinical setting. PET-CT: A Case-Based Approach, Second Edition, is a valuable resource for nuclear medicine practitioners, radiologists, and residents, as well as referring clinicians interested in learning more about how this imaging modality can be applied in their patient populations.  Peter S. Conti is a Professor of Radiology and the Director of the PET Imaging Science Center at the University of Southern California, and is a Fellow of both the American College of Radiology and American College of Nuclear Physicians. He is a pioneer in the development of the clinical applications of PET and PET-CT.