Non B cell-Derived Immunoglobulins The Structure, Characteristics and the Implication on Clinical Medicine
Produktdetaljer
Om bidragsyterne
Dr. Xiaoyan Qiu is a professor and director of Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center. Her research focuses on non B cell- derived immunoglobulins and cancer immunotherapy. She has published more than 80 articles on international peer-reviewed journals, such as Cancer Research, Leukemia and Cell Mol Immunol, etc.
This book has expanded classic concept of immunology. Immunoglobulins have been widely discovered to be produced by many non-B cells. The non B cell-derived Igs display multifunction, which not only includes antibody activities and cellular biological functions under physiological conditions, but also directly participate in the pathological process of malignant tumour and immune-related diseases. This book provides new perspectives and a solid foundation for medical students, basic and clinical scientists to re-understand and broaden the physiological and pathological significance of Ig.
Chapter 1 The history of appreciation of immunoglobulin and the discovery of non-B cell derived immunoglobulins.- Chapter 2 Expression profile of non B-Ig in different lineage cells.- Chapter 3 Unique V(D)J recombination characteristics and repertoire of non B-Ig.- Chapter 4 Unique regulation mechanismof non B-Ig gene.- Chapter 5 Unique structure and function of non B-Ig.- Chapter 6 Comparison of non B-Ig and B-Ig.- Chapter 7 Functionsand clinical relevanceof non-B cell derived immunoglobulin in liver.- Chapter 8 Significance of non-Bcell derived immunoglobulins in renal disease.- Chapter 9 Functions and clinical significance of myocardial cell-derived Immunoglobulins.- Chapter 10 Biological functions and clinical significance of intestinal non B-Immunoglobulins.- Chapter 11 Function of IgG and IgA in normal human skin.- Chapter 12 Significance of cancer-derived IgG in lung cancer.- Chapter 13 Significance of cancer-derived IgG in breast cancer.- Chapter 14 Significance of cancer-derived IgG in pancreatic cancer.- Chapter 15 Biological functions and clinical significance of non B-Ig in hemopoietic system.
This book has expanded classic concept of immunology. Immunoglobulins have been widely discovered to be produced by many non-B cells. The non B cell-derived Igs display multifunction, which not only includes antibody activities and cellular biological functions under physiological conditions, but also directly participate in the pathological process of malignant tumour and immune-related diseases. This book provides new perspectives and a solid foundation for medical students, basic and clinical scientists to re-understand and broaden the physiological and pathological significance of Ig.
Produktdetaljer
Om bidragsyterne
Dr. Xiaoyan Qiu is a professor and director of Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center. Her research focuses on non B cell- derived immunoglobulins and cancer immunotherapy. She has published more than 80 articles on international peer-reviewed journals, such as Cancer Research, Leukemia and Cell Mol Immunol, etc.