Contributors.- I Pathogenesis of Affective Disorders and Basic Mechanisms of Drug Action.- I.A. Animal Models and Antidepressant Predictability.- I.B. Monoamines and Neuropeptides.- I.C. Cholinergic Mechanisms.- I.D. Basic Mechanisms of Antidepressants and Anxiolytics.- I.E. Basic Mechanisms of Lithium Action.- I.F. Monoamine Oxidase Inhibitors.- II Neurobiology of Affective Disorders.- II. A. New Genetic Findings.- II.B. Biological Markers.- II.C. Chronobiology.- II.D. Psychoneuroendocrinology.- III Affective Disorders in Populations at Risk.- III.A. Affective Disorders and Suicide.- III.B. Affective Disorders During Childhood and Adolescence.- III.C. Affective Disorders in the Elderly.- III.D. Affective Disorders and Reproductive Cyclicity in Women.- IV Related Affective Syndromes.- IV.A. Anxiety Disorders.- IV.B. Obsessive Compulsive Disorder.- IV.C. Posttraumatic Stress Disorder.- IV.D. Anorexia and Bulimia.- IV.E. Schizoaffective Disorder.- V New Directions in Treatment.- V.A. Classification and Pharmacotherapy.- V.B. Anticonvulsants in Affective Disorder.- V.C. Treatment Strategies for Resistant Depression.- V.D. Antidepressants in Clinical Practice: Placebo Response in Depression.- V.D. Antidepressants in Clinical Practice: Plasma Levels of Antidepressants.- V.D. Antidepressants in Clinical Practice: Adverse Effects of Antidepressants.- V.E. GABA-Mimetics as Antidpressants.- V.F. Therapeutic Variations in ECT Administration.- V.G. Psychotherapy of Depression.

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