Preface xxi

Part 1: Introduction to the Fundamentals 1

1 Lipid-Based Nanocarriers as Drug Delivery System and Its Applications 3
Vikas Jain, Hitesh Kumar, Pallavi Chand, Sourabh Jain and Preethi S

2 Nanoparticulate Carriers—Versatile Delivery Systems 31
Ruchi Chawla, Varsha Rani and Mohini Mishra

3 Nanotools in Customized Drug Delivery System 55
Thirumalai Subramaniam K J, Gowthamarajan Kuppusamy, Arun Radhakrishnan and Veera Venkata Satyanarayana Reddy Karri

Part 2: Novel and Modernized Nanoscale Delivery Systems: Revolutionary Progress in the Field of Pharmacy 79

4 Dendrimers: Role in Novel Drug Delivery 81
Pooja Mittal, Ramit Kapoor and Brahmeshwar Mishra

5 Nanofibers in Drug Delivery 99
Dipak Kumar Sahu, Goutam Ghosh and Goutam Rath

6 Microbubbles used for Drug Delivery System 125
Hemraj Heer, Vishav Prabhjot Kaur, Sandeep Rathor, Sheikh Aamir and Charan Singh

7 Virosomes: A Viral Envelope System Having a Promising Application in Vaccination and Drug Delivery System 145
Ankit Kalra and Shilpa Sharma

8 Nanocarriers: A Tool for Effective Gene Delivery 161
Rita N. Wadetwar and Amita P. Godbole

9 Phytosomes—Nanoarchitectures’ Promising Clinical Applications and Therapeutics 187
Pankaj Pal, Vivek Dave, Shailendra Paliwal, Monika Sharma, Mrugendra B. Potdar and Avnica Tyagi

10 Saponin Stabilized Emulsion as Sustainable Drug Delivery System: Current Status and Future Prospects 217
Priyanka Yatham, Yogita Dahat, Arshad Khan, Rinku Baishya, Amit K. Srivastava and Deepak Kumar

11 Mono and Multi-Stimuli Responsive Polymers: Application as Intelligent Nano-Drug Delivery Systems 237
Archana Sidagouda Patil, Anand Panchakshari Gadad and Panchaxari Mallappa Dandagi

12 An Insight into Nanosomes: Potential Nanopharmaceutical Delivery System 267
Trishna Bal, Sandeep Garg, Aditya Dev Rajora, Shubha Rani Sharma and Harshita Harsh

13 Nano-Structures as Bioelectronics for Controlled Drug Delivery 285
Debabrata Ghosh Dastidar, Dipanjan Ghosh and Gopal Chakrabarti

14 Bioadhesive Nanoparticulate Drug Delivery System 309
Rajashree Shashidhar Masareddy, Archana Sidagouda Patil and Anand Panchakshari Gadad

Part 3: Understanding Targeted Delivery Systems 333

15 Nanopharmaceuticals: An Approach for Effective Management of Breast Cancer 335
Veena S. Belgamwar, Suchitra S. Mishra, Vidyadevi T. Bhoyar and Kunal B. Banode

16 Vaginal Nano-Based Drug Delivery System 357
Rita N. Wadetwar and Pranita S. Kanojiya

17 Recent Advances in Polymer-Modified Liposomes for Cancer Treatment 379
Swapnil Sharma, Akansha Bisht, Sanjana Tewari and Vivek Dave

18 Role of Nanomedicines in Neglected Tropical Diseases 407
Rahul Shukla, Atul Mourya, Mayank Handa and Rewati Raman Ujjwal

Part 4: Overview of Regulatory Affairs 447

19 Current Framework, Ethical Consideration and Future Challenges of Regulatory Approach for Nano-Based Products 449
Vivek Dave, Srija Sur and Nikita Gupta

Index 473

The book provides a systematic understanding of various novel drug delivery systems and their preparation, characterization and impressive range of applications.

These novel drug delivery systems demand a wide range of detailed knowledge of various drug delivery systems and their composition. Moreover, it is important to understand the properties of the various constituents of a nanoformulation that determine the preparative methods of the delivery systems and broadly ensure their properties. Nanopharmaceutical Advanced Delivery Systems covers a wide range of pharmaceutical topics required to appropriately perform and evaluate the biological and biopharmaceutical impact of nanopharmaceuticals in living systems

Nanopharmaceutical Advanced Delivery Systems provides in a single volume detailed descriptions of various delivery systems, their principles and how they are used for the treatment of specific diseases and is divided into four sections. The first section discusses the importance of novel drug delivery systems whereas the second section presents a detailed overview of the most advanced drug delivery systems such as microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions, etc. This section describes the major principles and techniques involved in the preparation of drug delivery systems in great detail and provides recently updated coverage of the important principles involved in the underlying science behind these therapeutic delivery systems. In this section, the authors focus on providing complete insight into the novel delivery systems along with their practical applications in the fields of health, medicine and therapeutics. The third section elaborates on the current evocative treatments of diverse diseases like cancer, topical diseases, tuberculosis, etc. The final section of the book provides a concise and informative description of the regulatory aspects of novel drug delivery systems that are followed in various countries

Audience

This book will be of immense interest and usefulness to biologists, pharmaceutical scientists, polymer chemists, materials scientists, bio and nanotechnologists, as well as those interested in biomaterials, target drug delivery, and controlled drug delivery.