Preface Peter Greenberg; 1. Clinical and prognostic characterization of Myelodysplastic Syndrome Peter Greenberg; 2. Morphologic classifications of Myelodysplastic Syndrome: French-American-British and the World Health Organization Richard Brunning; 3. Pathogenetic mechanisms underlying Myelodysplastic Syndrome Peter Greenberg; 4. Cytogenetic abnormalities in Myelodysplastic Syndrome Harold J. Olney and Michelle M. Le Beau; 5. Molecular mechanisms and gene expression patterns in Myelodysplastic Syndrome Wolf-Karsten Hofmann and Phillip Koeffler; 6. Immunologic mechanisms and treatment of Myelodysplastic Syndrome A. John Barrett, Elaine Sloand and Neal S. Young; 7. Biologically targeted therapies for Myelodysplastic Syndrome Andrew Buresh and Alan List; 8. Supportive care in Myelodysplastic Syndrome: hemopoietic cytokines and iron chelation therapy Jason Gotlib and Peter Greenberg; 9. Hematopoietic cell transplantation options in Myelodysplastic Syndrome Joachim Deeg and Bart Scott; 10. Health-related quality of life in Myelodysplastic Syndrome: conceptualization, measurement and implications Mary Thomas.