This volume describes immunological principles for tumour immunology, and discusses the contributions of modern immunology and molecular biology to research in tumour therapy. It provides a critical analysis of the progress and obstacles of major approaches in tumour immunotherapy.

Molecular basis of antigen recognition by T and B cells, C.A. Janeway; molecular mechanism of antigen processing and presentation, A. Rudensky; molecular and cellular basis of T cell costimulation, Y. Liu et al; cytokines as mediators in T cell activation and regulation, A. O'Garra; self-nonself discrimination of anti-tumour immune responses, S. Sarma and Y. Liu; processing, presentation and identification of tumour antigen, P. Srivastava; mutated oncogenes as targets for tumour immunotherapy, A. Frey; mechanisms of T cell recruitment into tumours, M. Maric and Y. Liu; T cell costimulation and tumour immunotherapy, L.-P. Chen; cytokine-based tumour immunotherapy, G. Forni; tumour vaccines, N. Restifo; novel and safer vectors for gene therapy, D. Meruelo; herpes simplex virus amplicon as vector for gene therapy and vaccine development, X.-L. Zhang.