I. General Concepts 1. Principles 2. Sources of exposures: Point vs Nonpoint Source Contamination 3. How chemicals distribute in the physical environment 4. How chemicals distribute in cells and simple organisms 5. How chemicals distribute in complex organisms II. Responses to chemical toxicants 6. Cellular responses to toxicants 7. Genotoxicity and epigenetics 8. Carcinogenesis 9. Disruption of cell signaling 10. Altered development and reproduction 11. Microbiome alterations and modulation of toxicity 12. Nanotoxicology III. Organ System Effects 13. Dermal system 14. Gastrointestinal system 15. Excretory system 16. Respiratory System 17. Cardiovascular system 18. Musculoskeletal system 19. Endocrine system 20. The immune system 21. Visual system 22. Nervous system IV. Ecosystems and Ecotoxicology 23. Organism vs population 24. Bioconcentration 25. Biomarkers V. Toxicology in the Home 26. Opiates and other therapeutics 27. Cleaning products 28. Petroleum products VI. Toxicology in the Community 29. Historical case studies 30. Social factors in community contamination VII. Forensic Toxicology VIII. Regulatory Toxicology 31. Toxicity testing 32. Tox21 33. Principles of Risk Assessment IX. Reference materials and websites 34. Information Resources in Toxicology, 4th edition. 35. National Toxicology Program 36. National Center for Toxicological Research 37. FDA 38. EPA

Covers major topics and newer areas in toxicology, including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity Includes a variety of perspectives to give a complete understanding of toxicology Written by specialists within each subject area, e.g., a chemical engineer, to ensure concepts are clearly explained