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Introduction to Drug Synthesis

Patrick Graham L.
Heftet / 2015 / Engelsk

Produktdetaljer

ISBN
9780198708438
Publisert
2015
Utgiver
Vendor
Oxford University Press
Vekt
1084 gr
Høyde
265 mm
Bredde
196 mm
Dybde
27 mm
Aldersnivå
UU, UP, 05
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
592

Forfatter
Patrick Graham L.

Om bidragsyterne

Graham Patrick is a lecturer in Organic Chemistry and Medicinal Chemistry at the University of the West of Scotland, Glasgow. He is the author of four other undergraduate textbooks covering medicinal chemistry and organic chemistry, including Introduction to Medicinal Chemistry, which is now in its fifth edition.

Introduction to Drug Synthesis

Patrick Graham L.
Heftet / 2015 / Engelsk
Patrick Graham L.
Heftet / 2015 / Engelsk
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Levering 7-20 dager
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An Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development. Written by an experienced and talented author to complement his existing An Introduction to Medicinal Chemistry, the book illustrates how organic synthesis makes important contributions throughout the drug design and discovery process - from the generation of novel drug structures to the improved efficiency of large scale synthesis. Avoiding excessively detailed descriptions of the underlying synthetic pathways, the book focuses on how synthesis can be used in a strategic way - how and why different synthetic approaches are adopted, and the pros and cons of each. With examples used extensively to illustrate the concepts presented, An Introduction to Drug Synthesis> is the ideal resource for any pharmaceutical or medicinal chemistry student who needs a thorough understanding of how the concepts of organic synthesis are applied to the development of therapeutic drugs. Online Resource Centre An Introduction to Drug Synthesis is supported by an Online Resource Centre featuring: For registered adopters: - Figures from the book in electronic format; For students: - A suite of multiple-choice questions to support the learning process; - Additional case studies - More detailed descriptions of key synthetic reactions, as a source of further reference.
Les mer
An Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development - from the generation of novel drug structures to the improved efficiency of large scale synthesis.
Les mer
PART A: Concepts ; 1. The drug discovery process ; 2. Drug synthesis ; 3. Retrosynthesis ; 4. Cyclic systems in drug synthesis ; 5. The synthesis of chiral drugs ; 6. Combinatorial and parallel synthesis ; PART B: Applications of drug synthesis in the drug development process ; 7. Synthesis of lead compounds ; 8. Analogue synthesis in drug design ; 9. Synthesis of natural products and their analogues ; 10. Chemical and process development ; 11. Synthesis of isotopically labelled compounds ; PART C: Design and synthesis of selected antibacterial agents ; 12. Design and synthesis of tetracyclines ; 13. Erythromycin and macrolide antibacterial agents ; 14. Quinolones and fluoroquinolones
Les mer
This is a well-written guide to many of the key concepts in the application of organic synthesis to drug discovery and development.
`The author has done a great job; it puts the context with the reaction, and fills a genuine gap in the market.' Dr John Spencer, University of Sussex `This is the only book on drug synthesis I have seen that has a chapter related to the drug discovery process, including basic biochemistry, physiology and pharmacology. The section on retrosynthesis is welcomed and makes this book stand out from other books on drug synthesis. Case studies using good examples are always difficult to find and the fact that there are many to choose from in this book is appreciated. I would certainly recommend this book, not only for undergraduate chemistry students but also for postgraduates.' Jordi Morral, University of Huddersfield `Recommended.' R. E. Buntrock, CHOICE
Les mer
An introduction to the central role of organic synthesis in the development of therapeutically useful drugs Written by an author whose name has become synonymous with clear and engaging explanations The extensive use of examples and case studies reinforces the relevance of the subject matter to the synthesis of drugs and highlights the different synthetic strategies available An Online Resource Centre provides additional teaching and learning resources to augment the printed text
Les mer
Graham Patrick is a lecturer in Organic Chemistry and Medicinal Chemistry at the University of the West of Scotland, Glasgow. He is the author of four other undergraduate textbooks covering medicinal chemistry and organic chemistry, including Introduction to Medicinal Chemistry, which is now in its fifth edition.
Les mer
An introduction to the central role of organic synthesis in the development of therapeutically useful drugs Written by an author whose name has become synonymous with clear and engaging explanations The extensive use of examples and case studies reinforces the relevance of the subject matter to the synthesis of drugs and highlights the different synthetic strategies available An Online Resource Centre provides additional teaching and learning resources to augment the printed text
Les mer

Relaterte produkter

An Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development. Written by an experienced and talented author to complement his existing An Introduction to Medicinal Chemistry, the book illustrates how organic synthesis makes important contributions throughout the drug design and discovery process - from the generation of novel drug structures to the improved efficiency of large scale synthesis. Avoiding excessively detailed descriptions of the underlying synthetic pathways, the book focuses on how synthesis can be used in a strategic way - how and why different synthetic approaches are adopted, and the pros and cons of each. With examples used extensively to illustrate the concepts presented, An Introduction to Drug Synthesis> is the ideal resource for any pharmaceutical or medicinal chemistry student who needs a thorough understanding of how the concepts of organic synthesis are applied to the development of therapeutic drugs. Online Resource Centre An Introduction to Drug Synthesis is supported by an Online Resource Centre featuring: For registered adopters: - Figures from the book in electronic format; For students: - A suite of multiple-choice questions to support the learning process; - Additional case studies - More detailed descriptions of key synthetic reactions, as a source of further reference.
Les mer
An Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development - from the generation of novel drug structures to the improved efficiency of large scale synthesis.
Les mer
PART A: Concepts ; 1. The drug discovery process ; 2. Drug synthesis ; 3. Retrosynthesis ; 4. Cyclic systems in drug synthesis ; 5. The synthesis of chiral drugs ; 6. Combinatorial and parallel synthesis ; PART B: Applications of drug synthesis in the drug development process ; 7. Synthesis of lead compounds ; 8. Analogue synthesis in drug design ; 9. Synthesis of natural products and their analogues ; 10. Chemical and process development ; 11. Synthesis of isotopically labelled compounds ; PART C: Design and synthesis of selected antibacterial agents ; 12. Design and synthesis of tetracyclines ; 13. Erythromycin and macrolide antibacterial agents ; 14. Quinolones and fluoroquinolones
Les mer
This is a well-written guide to many of the key concepts in the application of organic synthesis to drug discovery and development.
`The author has done a great job; it puts the context with the reaction, and fills a genuine gap in the market.' Dr John Spencer, University of Sussex `This is the only book on drug synthesis I have seen that has a chapter related to the drug discovery process, including basic biochemistry, physiology and pharmacology. The section on retrosynthesis is welcomed and makes this book stand out from other books on drug synthesis. Case studies using good examples are always difficult to find and the fact that there are many to choose from in this book is appreciated. I would certainly recommend this book, not only for undergraduate chemistry students but also for postgraduates.' Jordi Morral, University of Huddersfield `Recommended.' R. E. Buntrock, CHOICE
Les mer
An introduction to the central role of organic synthesis in the development of therapeutically useful drugs Written by an author whose name has become synonymous with clear and engaging explanations The extensive use of examples and case studies reinforces the relevance of the subject matter to the synthesis of drugs and highlights the different synthetic strategies available An Online Resource Centre provides additional teaching and learning resources to augment the printed text
Les mer
Graham Patrick is a lecturer in Organic Chemistry and Medicinal Chemistry at the University of the West of Scotland, Glasgow. He is the author of four other undergraduate textbooks covering medicinal chemistry and organic chemistry, including Introduction to Medicinal Chemistry, which is now in its fifth edition.
Les mer
An introduction to the central role of organic synthesis in the development of therapeutically useful drugs Written by an author whose name has become synonymous with clear and engaging explanations The extensive use of examples and case studies reinforces the relevance of the subject matter to the synthesis of drugs and highlights the different synthetic strategies available An Online Resource Centre provides additional teaching and learning resources to augment the printed text
Les mer

Produktdetaljer

ISBN
9780198708438
Publisert
2015
Utgiver
Vendor
Oxford University Press
Vekt
1084 gr
Høyde
265 mm
Bredde
196 mm
Dybde
27 mm
Aldersnivå
UU, UP, 05
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
592

Forfatter
Patrick Graham L.

Om bidragsyterne

Graham Patrick is a lecturer in Organic Chemistry and Medicinal Chemistry at the University of the West of Scotland, Glasgow. He is the author of four other undergraduate textbooks covering medicinal chemistry and organic chemistry, including Introduction to Medicinal Chemistry, which is now in its fifth edition.

Relaterte produkter