Over the years, interventional radiology has developed many effective and less invasive procedures. As the number and types of interven tions increase, radiologists are becoming more and more involved in clinical patient care. This includes pre-interventional patient workup, sophisticated medical therapy and monitoring during interventions, regular inpatient rounds and complete follow-up management. Therefore interventional radiologists are faced with a broad spectrum of clinical and pharmacological questions. Adjunctive medical therapy should increase the patient's comfort, should improve the success rates, and should further reduce the risks of the procedures. In order to fulfill our responsibility to the patients, a profound knowledge of certain drugs is indispensable. This in cludes, for example, sedatives, analgesics, cardiovascular drugs and agents to prevent infections, thromboembolic complications or restenoses. Moreover, a good monitoring system during complex procedures will increase the safety of radiological interventions. These topics and several more have been presented and discussed during an international symposium in Basel, Switzerland, in January 1992. It is the benefit of the authors, that all these results could be published shortly after the event. Connected with our thanks to all the co-workers the editors hope to find this publication assisting an increasing number of safe interventions.

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This includes pre-interventional patient workup, sophisticated medical therapy and monitoring during interventions, regular inpatient rounds and complete follow-up management. Adjunctive medical therapy should increase the patient's comfort, should improve the success rates, and should further reduce the risks of the procedures.

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Pharmacologic Bases of Sedatives, Analgesics, and Anesthetic Agents.- Analgesia and Sedation in the Hands of the Interventional Radiologist.- Sedation and Anesthesia in Radiologic Interventions.- Special Aspects of Analgesia, Sedation, and Anesthesia in Children.- Pathophysiologic Aspects of Blood-Pressure Dysregulation, Hypovolemia, and Microcirculation.- Treatment of Disturbances in Blood-Pressure Regulation, Volume Homeostasis, and Microcirculation During Interventional Radiologie Procedures.- Equipment and Training of Staff for Patient Monitoring in Interventional Radiology.- Technical Monitoring During Radiologic Interventions — What Can Be Done and What Must Be Done.- Monitoring of Vital Functions in the Course of Interventional Radiology Procedures.- Pathophysiology of Blood Clotting in Relation to Radiologic Interventions.- Use of Anticoagulants and Clotting Agents — Procedures in Patients with Pre-existing Coagulation Disorders.- Drug Therapy During Venous Interventions and Vena Cava Filter Procedures.- Adjunctive Medication, Therapy, and Special Monitoring in Embolization Procedures.- Drug Therapy, Monitoring, and Function Testing in Neuroradiologic Interventions.- Drug Therapy in Computed-Tomography-Guided Interventional Procedures.- The Pathophysiology of Contrast Media Use.- Improving Contrast Media Tolerance — Pharmacologic Options and Treatment of Allergic Reactions.- Type and Incidence of Serious Complications During and After Interventional Radiologic Procedures.- Treatment of Cardiovascular Complications During Radiologic Interventions.- Incidence and Treatment of Complications During Neuroradiologie Interventions.- Pathophysiology of Restenosis After Percutaneous Transluminal (Coronary) Angioplasty.- Pharmacologie Prevention of RestenosisFollowing Angioplasty.

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