Provides surgical pathologists with expert reference material. The lesions described relate principally to medical non-neoplastic conditions as exemplified by the first three Fascicles on endocrine, pulmonary, and skin diseases. Many of these lesions represent complex entities and when appropriate the authors have included contributions from internists, radiologists, and surgeons.

Chapters: 1. Pituitary Gland - Normal Pituitary Gland * reactive Changes * Hereditary and Developmental Disorders * Circulatory Disorders * Metabolic Disorders * Infectious Diseases * Autoimmune Diseases * Pituitary Cysts * Pituitary Hyperplasia. 2. Parathyroid Gland - Normal Parathyroid Gland * Overview of Hypercalcemia and Hypocalcemia * Hereditary and Developmental Disorders * Cysts and Hamartomas * Hyperplasia * Secondary and Tertiary Hyperparathyroidism. 3.Thyroid Gland - Normal Thyroid Gland * Hereditary and Developmental Disorders * Miscellaneous Conditions * Metabolic Diseases Infections and Granulomatous Diseases * Autoimmune Thyroid Disease * Simple Multinodular Dyshormonogenetic and Diffuse Toxic Goiters * C-cell Hyperplasia. 4.Adrenal Gland - Normal Adrenal Gland * Reactive Hereditary and Developmental Disorders * Exogenous Injury * Infectious Diseases and Miscellaneous Conditions * Adrenal Cortical Hypofunction * Other Conditions Associated with Hypofunction * Adrenal Cortical Nodules and Hyperplasia * Adrenal Medullary Hyperplasia. 5. Diffuse Neuroendocrine System - Embryology and Anatomy * Histology * Methods Used to Characterize DNES Cells * Hypofunction in Cells and Tissues of the DNES * DNES Cell Hyperplasia