DNA-encoded libraries have numerous advantages over traditional screening methods, including easy identification of compounds and the large quantity of compounds that can be screened simultaneously.
This book provides a comprehensive guide to the implementation of DNA-encoded library technology (DELT) in drug discovery for screening and hit validation, illustrated with successful case studies.
A valuable resource for researchers in drug discovery, this book is complete with successful case studies to illustrate the best practice in implementation and operation of DELT.
Les mer
This book provides a comprehensive guide to to the implementation of DNA-encoded library technology (DELT) in drug discovery for screening and hit validation.
Overview of Affinity-based DEL Selections with Select Target Types and AchievementsMachine Learning with DEL Selection Data and for DEL designOne bead one compound (OBOC) DELs for Biochemical ScreensLive cell-based DEL SelectionsOn-DNA Medicinal Chemistry: Focused libraries, fragment expansion, and hit optimizationDELs with Covalent WarheadsApplication of DELs for E3 Ligase Ligand and PROTAC development
Les mer
Produktdetaljer
ISBN
9781788014878
Publisert
2025-02-21
Utgiver
Vendor
Royal Society of Chemistry
Vekt
420 gr
Høyde
234 mm
Bredde
156 mm
Dybde
12 mm
Aldersnivå
UP, 05
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
176