Part I Getting Started 1 Leadership and Management: The Principal Investigator and Research Coordinator 2 Roles: Why a Research Coordinator is Critical 3 Hiring: Characteristics of a Highly Qualified Research Coordinator 4 Growth: From 0 to 100, Real Quick! Part II What Every Research Coordinator Needs to Know 5 What is Evidence-Based Medicine? 6 Randomized Controlled Trials 7 Observational Studies 8 Surveys 9 Qualitative Studies 10 Principles of Good Clinical Practice and Research Conduct Part III From Idea to Study Start-Up 11 Principles of Grant Writing: Tips for a Successful Experience 12 Dollars and "Sense": A Guide to Research Finances 13 Maintaining Records and the Trial Master File 14 Ethics Submissions 15 The Basics of Research Contracts 16 How to Start-Up a Study Part IV Study Execution and Close-Out 17 Screening and Recruiting Participants 18 Obtaining Informed Consent 19 Collecting Data: Paper and Electronic Data Capture Systems 20 Follow-Up: Why It Is Important and How to Minimize Loss to Follow-Up 21 How to Close Out a Study 22 Knowledge Dissemination: Getting the Word Out! Part V Advanced Principles of Research Coordination 23 Regulatory Trials: Key Differences from Standard Trials 24 How to Survive a Site Audit 25 Monitoring in a Clinical Study: Why and How? 26 Managing Large Studies: Organization and Committees 27 International Research: Challenges and Successes Part VI A Coordinator's Toolbox Toolbox A Toolbox B Toolbox C Toolbox D Toolbox E Toolbox F1 Toolbox F2 Toolbox F3 Toolbox F4 Toolbox F5 Toolbox F6 Toolbox F7 Toolbox F8 Toolbox F9 Toolbox F10 Toolbox F11 Toolbox G