Contributors iv Preface to the Fifth Edition v 1 Iron Deficiency Anaemia 1 Catherine Booth and Drew Provan 2 Macrocytic Anaemia 7 Samah Babiker and Nita Prasannan 3 The Hereditary Anaemias 13 Rachel Kesse- Adu 4 Polycythaemia Vera Essential Thrombocythaemia and Myelofibrosis 19 Anna L. Godfrey and Claire Harrison 5 Chronic Myeloid Leukaemia 25 Hugues de Lavallade 6 The Acute Leukaemias 31 Michael Austin and Bela Patel 7 Platelet Disorders 39 Marie A. Scully and John Paul Westwood 8 Adult Myelodysplastic Syndrome 47 Sally B. Killick 9 Myeloma and Other Plasma Cell Dyscrasias 53 Sally Moore and Karthik Ramasamy 10 Bleeding Disorders Thrombosis and Anticoagulation 59 Vickie McDonald 11 Lymphoma 65 Karen Stanley and David Wrench 12 Stem Cell Transplantation 81 Michelle Escebedo- Cousin and Kirsty Thomson 13 Cellular Therapies 87 Reuben Benjamin 14 Paediatric Haematology 91 John D. Grainger and Lianna Reynolds 15 Amyloidosis with a Focus on Systemic Light Chain Amyloidosis 101 Ayesha Shameem Mahmood 16 Haematological Emergencies 109 Vered Stavi and Igor Novitzky- Basso Index 119

ABC of Clinical Haematology An essential guide and introduction to the diagnosis, treatment and management of disorders across the breadth of clinical haematology Extensively revised, this 5th edition of ABC of Clinical Haematology covers all aspects of contemporary haematology, providing the basic science behind the disease and diagnostic aspects, along with up to date management. The text assumes little prior haematology knowledge, enabling clear understanding by non-experts, including medical students and nurses. Full colour illustrations and text boxes highlighting important learning points together enable more efficient reader comprehension. ABC of Clinical Haematology covers: Iron deficiency anaemia, macrocytic anaemia, hereditary anaemias, polycythaemia vera, essential thrombocythaemia, and myelofibrosis Chronic myeloid leukaemia, acute leukaemias, lymphoma, stem cell transplantation, cellular therapies, adult myelodysplastic syndrome, and myeloma Bleeding disorders, thrombosis, anticoagulation, and paediatric haematology, platelet disorders Amyloidosis, with focus on systemic light chain amyloidosis, and haematological emergencies New tests, treatments, and management solutions that are now available for certain conditions, especially common blood related disorders With contributions from leading experts in their respective fields, ABC of Clinical Haematology, Fifth Edition provides an ideal reference for primary care practitioners and other healthcare professionals working with patients who have blood related problems. About the ABC series The ABC series has been designed to help you access information quickly and deliver the best patient care, and remains an essential reference tool for GPs, junior doctors, medical students and healthcare professionals. Now offering over 80 titles, this extensive series provides you with a quick and dependable reference on a range of topics in all the major specialties. The ABC series is the essential and dependable source of up-to-date information for all practitioners and students in primary healthcare. To receive automatic updates on books and journals in your specialty, join our email list. Sign up today at www.wiley.com/email