This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing.
Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.
Les mer
This book describes the processes that are involved in the development of new drugs. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery.
Les mer
Chapter 1: Historical Perspective of Drug Discovery and Development.- Chapter2: Natural Products and Drug Discovery.- Chapter 3: The Concept Of Receptors And Molecules Interaction In Drug Discovery And Development.- Chapter 4: Chemical Structure and Stereochemistry.- Chapter 5:Biased Agonism:Renewing GPCR's targetability.- Chapter 6: Computer Aided Drug Discovery.- Chapter 7: Pharmacological screening of novel chemical entities.- Chapter 8:Drug Target Identification and Validation.- Chapter 9: Genetics and Drug Discovery.- Chapter 10: Stem Cells and Therapeutics.- Chapter 11: Pharmacokinetics.- Chapter 12: Regulatory Toxicological Testing.- Chapter 13: Nanotoxicology and Regulatory Requirements.- Chapter 14: Clinical Trials in Industrial Drug Development.- Chapter 15:Pharmacovigilance.- Chapter 16: Regulatory Process for New Drug Approval in India.- Chapter 17: Pharma Industry, Academia, Regulatory Authorities, and End-user Interaction.- Chapter 18: Statistics.
Les mer
This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing.Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.
Les mer
Explains the various phases of drug discovery and development Simplifies the complex process of drug discovery and development Establishes a connect between academia and industry
Produktdetaljer
ISBN
9789811555367
Publisert
2022-02-17
Utgiver
Vendor
Springer Verlag, Singapore
Høyde
235 mm
Bredde
155 mm
Aldersnivå
Research, P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Redaktør