The Oxford Handbook of Skepticism features twenty-six newly commissioned chapters by top figures in the field. It explains important kinds of skeptical reasoning, examines the responses to skeptical arguments, and delves into the important contemporary issues revolving around skepticism.

Introduction - John Greco ; Part One. Varieties of Skepticism and Skeptical Arguments ; 1. The Pyrrhonian Problematic- Markus Lammenranta ; 2. The Problem of the Criterion- Richard Fumerton ; 3. Cartesian Skepticism: Arguments and Antecedents- Jose Luis Bermudez ; 4. Hume's Skepticism- Michael Williams ; 5. Skepticism about the External World- John Greco ; 6. Skepticism about Induction- Weintraub ; 7. Skepticism about A Priori Justification: Self-evidence, Defeasibility, and Cogito Propositions- Robert Audi ; 8. Moral Realism, Quasi-Realism and Skepticism- Terence Cuneo ; 9. Religious Skepticism - Paul K. Moser ; 10. Live Skeptical Hypotheses - Bryan Frances ; Part Two. Responses to Skepticism ; 11. Berkeley's Treatment of Skepticism - George Pappas ; 12. Kant's Response to Skepticism- Robert Stern ; 13. Reid's Response to Skepticism- James Van Cleve ; 14. Peirce and Skepticism - Christopher Hookway ; 15. Moore's Common Sense Response- Noah Lemos ; 16. Austin's Way with Skepticism - Mark Kaplan ; 17. Wittgentein on Certainty -Marie McGinn ; 18. Relativism as a Response to Skepticism- Peter J. Graham ; Part Three. Contemporary Issues ; 19. Ascriber Contextualism- Stewart Cohen ; 20. Sensitivity, Safety, and Anti-Luck Epistemology - Duncan Pritchard ; 21. Closure and Alternative Possibilities - Jonathan Kvanvig ; 22. Contemporary Responses to the Regress Argument- Peter D. Klein ; 23. Externalist Responses to Skepticism -Michael Bergmann ; 24. Internalist Responses to Skepticism - Jonathan Vogel ; 25. Virtue-theoretic Responses to Skepticism - Guy Axtell ; 26. Disjunctivism and Skepticism- Alan Millar