Holistic medicine is: A clinical discipline that integrates both Eastern and Western medical methods and knowledge systems into oneAn evidence-based medicine that simultaneously embodies both a holistic approach and personalized principlesThe most straightforward form of medicine that adheres to scientific standards and effectively meets the needs of humanityIn recent years, the integrated research on living organisms initiated by systems biology, along with the efforts of precision medicine to tailor treatment plans based on the individual characteristics of each patient, have opened up the process of modern biology and medicine returning to the ideas of Chinese medical traditions. Under the larger perspective of the development and evolution of Eastern and Western medicine, biology, and even natural science for hundreds of years, this book follows the evolution of modern scientific methods and reveals the inevitable trend of future medicine—holistic medicine. Holistic medicine is a medical system that fully integrates Chinese and Western medical methods and knowledge systems and conforms to scientific norms. It is an evidence-based medicine that embodies the holistic concept and individualized principles. This book outlines the method and theoretical framework of holistic medicine, and provides the method of constructing the theoretical system and using it to achieve the best regulation of diseases. It can be expected that holistic medicine will become the mainstream medicine in the 21st century.