The historical approach to the interpretation of physical, chemical and biological phenomena has been to consider relationships with causative factors that can be reduced to linearity allowing simple and direct interpretation. However, it is increasingly evident that there is often more information in the data than linear interpretations allow. The current capacity for computers to assist in identifying non-linear relationships allows greater interpretation of data which illuminates the phenomena allowing the information to be translated into knowledge that can be used wisely to promote various desirable pharmaceutical outcomes. This short volume is intended to stimulate the reader to contemplate research and development areas in which the data might be more accurately interpreted to allow greater understanding and ultimately control of the pharmaceutically complex phenomena.
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The historical approach to the interpretation of physical, chemical and biological phenomena has been to consider relationships with causative factors that can be reduced to linearity allowing simple and direct interpretation.
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The nature of complexity and relevance to the pharmaceutical sciences.- Phenomena in Physical and Surface Chemistry.- Solid State Pharmaceuticals: Solving Complex Problems in Preformulation and Formulation.- Considerations in monitoring and controlling pharmaceutical manufacturing.- Pharmacokinetics and pharmacodynamics.- Impact of complexity on population Biology.- Conclusion.

     

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The historical approach to the interpretation of physical, chemical and biological phenomena has been to consider relationships with causative factors that can be reduced to linearity allowing simple and direct interpretation. However, it is increasingly evident that there is often more information in the data than linear interpretations allow. The current capacity for computers to assist in identifying non-linear relationships allows greater interpretation of data which illuminates the phenomena allowing the information to be translated into knowledge that can be used wisely to promote various desirable pharmaceutical outcomes. This short volume is intended to stimulate the reader to contemplate research and development areas in which the data might be more accurately interpreted to allow greater understanding and ultimately control of the pharmaceutically complex phenomena.
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Describes topics that indicate a need for a non-linear interpretation if they are to be characterized accurately, understood fully and potentially controlled or modulated in the service of improved therapeutic strategies Promotes discussion of phenomena leading to pharmacological effect and the complex interactions ultimately resulting in improved disease control and health maintenance Includes supplementary material: sn.pub/extras
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Product details

ISBN
9781441978554
Published
2010-12-20
Publisher
Vendor
Springer-Verlag New York Inc.
Height
203 mm
Width
127 mm
Age
Research, P, 06
Language
Product language
Engelsk
Format
Product format
Heftet

Biographical note

Dr. Anthony Hickey is Professor of Molecular Pharmaceutics and Biomedical Engineering at the University of North Carolina at Chapel Hill. He is a fellow of the Institute of Biology, American Association of Pharmaceutical Scientists and the American Association for the Advancement of Science. He has published several edited and authored volumes in the fields of pharmaceutical aerosols, process engineering and particulate science.

Dr. Hugh Smyth is Assistant Professor of Pharmaceutics at the University of Texas, Austin. He is a recipient of the Young Investigator in Pharmaceutics and Pharmaceutical Technology Award of the American Association of Pharmaceutical Scientists and has edited a volume on pulmonary drug delivery. Drs. Hickey and Smyth share a research interest in the delivery of drugs to the lungs for the treatment and prevention of a number of diseases.