Product details
ISBN
9780443235856
Published
2025-07-25
Publisher
Elsevier - Health Sciences Division; Elsevier - Health Sciences Division
Weight
710 gr
Height
229 mm
Width
152 mm
Age
P, 06
Language
Product language
Engelsk
Format
Product format
Heftet
Number of pages
438
Author
Biographical note
Dr Qiao-Hong Chen received her PhD degree in Medicinal Chemistry from Sichuan University, China. Appointed as a Lecturer in 2001, She was promoted to the position of Full Professor in 2003 at Sichuan University. She was a Postdoctoral Fellow for three years at the University of Alberta in Canada and a Senior Research Fellow for six years at Virginia Tech. She joined Fresno State in 2012. Her research interests focus on natural products-based anticancer agents. She has published 152 peer-reviewed scientific publications, as well as 5 book chapters.
Anti-Prostate Cancer Agents walks the readers through the anti-prostate cancer drug development pipeline from early discovery/design to clinical studies/applications. This book covers discovery/design, synthetic studies, preclinical evaluation, mechanism of action, structure-activity relationships, clinical studies/applications of anti-prostate cancer agents.
This book provides insight on how the design and discovery process of anti-prostate cancer agents have evolved from androgen deprivation therapy to current androgen receptor antagonists/degraders. So far, no book focusing on the topic has been published.
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1. Introduction: Overview of Prostate Cancer
2. Why has one got prostate cancer?
3. Androgen Deprivation Therapy
4. Anti-prostate cancer agents interacting with topoisomerase
5. Microtubule-Stabilizing Compounds as Anti-Prostate Cancer Agents
6. Androgen/Androgen Receptor Signaling Pathway and Prostate Cancer
7. Anti-Prostate Cancer Agents Suppressing Androgen Biosynthesis
8. First Generation Nonsteroidal Androgen Receptor Antagonists
9. Second Generation Nonsteroidal Androgen Receptor Antagonists
10. Anti-Prostate Cancer Agents Interacting with N-Terminal Domain of Androgen Receptor
11. Androgen Receptor Degraders as Anti-Prostate Cancer Agents
12. Radiotherapeutics for treatment of Prostate Cancer
13. Immunotherapy for Prostate Cancer
14. Radiosensitizer for prostate cancer
15. Anti-Prostate Cancer Agents Targeting Prostate-Specific Membrane Antigen
16. Anti-Prostate Cancer Agents Targeting Poly(ADP-Ribose)Polymerase
17. Combined Anti-Prostate Cancer Agents
18. Future Directions
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Provides insights as to how the anti-prostate cancer drugs evolved from androgen deprivation therapy to current androgen receptor antagonists/degraders
Provides insight on how the design and discovery process of anti-prostate cancer agents have evolved
Explore the anti-prostate cancer drug development pipeline from early discovery/design to clinical studies/applications
Highlight the molecular targets and mechanism of action for anti-prostate cancer agents
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Product details
ISBN
9780443235856
Published
2025-07-25
Publisher
Elsevier - Health Sciences Division; Elsevier - Health Sciences Division
Weight
710 gr
Height
229 mm
Width
152 mm
Age
P, 06
Language
Product language
Engelsk
Format
Product format
Heftet
Number of pages
438
Author