This book constitutes the refereed proceedings of the 15th International Conference on Reversible Computation, RC 2023, held in Giessen, Germany, during July 18–19, 2023.The 11 full papers and 3 short papers included in this book were carefully reviewed and selected from 19 submissions. Quantum Computing;

​Invited Paper.- Energy complexity of computation.- Foundations.- Replications in Reversible Concurrent Calculi.- Towards a Taxonomy for Reversible Computation Approaches.- Computational Complexity of Reversible Reaction Systems.- Reversible Programming.- Optimization of Reversible Control Flow Graphs.- Tail recursion transformation for invertible functions.- Saving Memory Space in Deep Neural Networks by Recomputing: A Survey.- Towards a Dereversibilizer: Fewer Asserts, Statically.- Quantum Computing.- Quantum String Matching Unfolded and Extended.- Optimizing Quantum Space using Spooky Pebble Games.- Uncomputation in the Qrisp high-level Quantum Programming Framework.- Quantum Circuits.- Improved Synthesis of Tooli-Hadamard Circuits.- Implementation of a Reversible Distributed Calculus.- Improved Cost-Metric for Nearest Neighbor Mapping of Quantum Circuitsto 2-Dimensional Hexagonal Architecture.- Exploiting the Benefits of Clean Ancilla Based Toffoli Gate Decomposition Across Architectures.